Highly Stable Zr(IV)-Based Metal–Organic Frameworks for Chiral Separation in Reversed-Phase Liquid Chromatography

• Published in: Journal of the American Chemical Society Vol. 143; no. 1; pp. 390 - 398
• Main Authors: Jiang, Hong, Yang, Kuiwei, Zhao, Xiangxiang, Zhang, Wenqiang, Liu, Yan, Jiang, Jianwen, Cui, Yong
• Format: Journal Article
• Language: English
• Published: WASHINGTON Amer Chemical Soc 13.01.2021
• Subjects: Chemistry; Chemistry, Multidisciplinary; durability; enantiomers; influenza; ligands; pharmacology; Physical Sciences; reversed-phase high performance liquid chromatography; reversed-phase liquid chromatography; Science & Technology; stereoselectivity; topology; DESIGN; RECOGNITION; MOF; ENANTIOMERS; RESOLUTION; CHEMISTRY; DERIVATIVES; RACEMIC AMINO-ACIDS

Separation of racemic mixtures is of great importance and interest in chemistry and pharmacology. Porous materials including metal-organic frameworks (MOFs) have been widely explored as chiral stationary phases (CSPs) in chiral resolution. However, it remains a challenge to develop new CSPs for reve...