Presence of the vesicular inhibitory amino acid transporter in GABAergic and glycinergic synaptic terminal boutons

• Published in: Journal of cell science Vol. 112 ( Pt 6); no. 6; pp. 811 - 823
• Main Authors: Dumoulin, A, Rostaing, P, Bedet, C, Lévi, S, Isambert, M F, Henry, J P, Triller, A, Gasnier, B
• Format: Journal Article
• Language: English
• Published: England 15.03.1999
• Subjects: Amino Acid Transport Systems; Animals; Antibody Specificity; Carrier Proteins - analysis; Cells, Cultured; COS Cells; Embryo, Mammalian; gamma-Aminobutyric Acid - analysis; Glycine - analysis; Immunohistochemistry; Mice; Microscopy, Immunoelectron; Neurons - cytology; Neurons - ultrastructure; Presynaptic Terminals - classification; Presynaptic Terminals - ultrastructure; Rabbits; Rats; Rats, Sprague-Dawley; Spinal Cord - cytology; Spinal Cord - ultrastructure; Transfection; Vesicular Inhibitory Amino Acid Transport Proteins; Vesicular Transport Proteins

The characterization of the Caenorhabditis elegans unc-47 gene recently allowed the identification of a mammalian (gamma)-amino butyric acid (GABA) transporter, presumed to be located in the synaptic vesicle membrane. In situ hybridization data in rat brain suggested that it might also take up glyci...