Performance evaluation of a particle-enhanced turbidimetric cystatin C assay using the Abbott Aeroset analyser and assessment of cystatin C-based equations for estimating glomerular filtration rate in chronic kidney disease

• Published in: Nephrology, dialysis, transplantation Vol. 25; no. 5; pp. 1489 - 1496
• Main Authors: Sun, Yanhong, Jiang, Tang, Zeng, Zhijie, Chen, Peisong
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.05.2010
• Subjects: Adolescent; Adult; Aged; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Chronic Disease; chronic kidney disease; cystatin C; Cystatin C - blood; Emergency and intensive care: renal failure. Dialysis management; Female; Glomerular Filtration Rate; Glomerulonephritis; Humans; Intensive care medicine; Kidney Diseases - physiopathology; Male; Medical sciences; Middle Aged; Nephelometry and Turbidimetry - methods; Nephrology. Urinary tract diseases; Nephropathies. Renovascular diseases. Renal failure; Particle; Kidney disease; Cystatin; Extrarenal dialysis; cystatin C; chronic kidney disease; Urinary system disease; Glomerular filtration; Hemodialysis; glomerular filtration rate; Renal failure

Introduction. Measurement of glomerular filtration rate (GFR) is critical for the diagnosis and stratification of chronic kidney disease (CKD). Recent studies have shown that cystatin C is superior to creatinine for the detection of impaired GFR, and several cystatin C-based equations for estimating...