Cell membrane-camouflaged nanoparticles as drug carriers for cancer therapy

• Published in: Acta biomaterialia Vol. 105; pp. 1 - 14
• Main Authors: Xu, Cheng-Hui, Ye, Peng-Ju, Zhou, Yang-Chun, He, Dong-Xiu, Wei, Hua, Yu, Cui-Yun
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 15.03.2020; Elsevier BV
• Subjects: Animals; Biomimetic nanoparticle; Biomimetics; Cancer therapies; Cancer therapy; Cell membrane; Cell Membrane - chemistry; Cell membranes; Drug carriers; Drug Carriers - chemistry; Drug delivery; Drug delivery systems; Humans; Membranes; Mesenchymal Stem Cells - metabolism; Nanomaterials; Nanomedicine; Nanoparticles; Nanoparticles - chemistry; Nanotechnology; Neoplasms - drug therapy; Physicochemical properties; Properties (attributes); Static Electricity; Translocation; EM-JPMs; Cell membrane; PNPs; EPR; HNPs; CMCNPs; MHC; HIF-1α; PEG-PDLLA; MSCs; VEGFR; Biomimetic nanoparticle; PBS; TRAIL; P-gp; LFA-1; PLT-MNs; H&E; SIRPα; DOX; WBCNPs; MPCM-MSNCs; WBCs; ICNPs; MEL; PCL; CXCR; NMNPs; PECAM-1; MPCM-AuNSs; SDF-1; Drug delivery; DHCNPs; RBCNPs; PTT; DMEM; DDS; MDR1; PDGFR; TGF-β; SCMGs-DOX; FRET; Nanomedicine; CCNPs; CTCs; PDT; MSCNPs; RBCs; VEGF; ICG; NPs; VCAM-1; PEG; PLGA; Cancer therapy; NIR; PDGF; MPLA; TEM

The translocation of natural cell membranes to the surface of synthetic nanoparticles, which allows man-made vectors to share merits and functionalities created by nature, has been a hot subject of research in the past decade. The resulting biomimetic nanoparticles not only retain the physicochemica...