A sesquiterpenoid tropolone and 1,2,3,4-tetrahydronaphthalene derivatives from Olax imbricata roots

• Published in: Fitoterapia Vol. 132; pp. 1 - 6
• Main Authors: Nguyen, Huong T.M., Vo, Nga T., Huynh, Suong T.M., Do, Lien T.M., Aree, Thammarat, Tip-pyang, Santi, Phan, Cam-Tu D., Trung, Nguyen T., Nguyen, Phung K.P.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.01.2019; Elsevier Science Ltd
• Subjects: Biotechnology; Cancer; Circular dichroism; Configurations; Cytotoxicity; Derivatives; Dichroism; Experiments; NMR; Nuclear magnetic resonance; Olax imbricata; Olaximbrisides A–D; Roots; Sesquiterpenoid; Tetrahydronaphthalene; Tropolone; Tumor cell lines; X-ray diffraction; Olax imbricata; Tropolone; Cytotoxicity; Olaximbrisides A–D; Sesquiterpenoid; Tetrahydronaphthalene

The methanol extract of Olax imbricata roots afforded one new sesquiterpenoid tropolone and three new 1,2,3,4-tetrahydronaphthalene derivatives, olaximbrisides A–D (1–4). Their structures were determined by 1D and 2D NMR experiments in combination of HRESIMS. The relative configurations were assigne...