Allergenicity assessment of Buchanania lanzan protein extract in Balb/c mice

• Published in: International immunopharmacology Vol. 63; pp. 170 - 182
• Main Authors: Kumar, Sachin, Sharma, Akanksha, Gupta, Rinkesh Kumar, Verma, Ajay Kumar, Dwivedi, Premendra D.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.10.2018; Elsevier BV
• Subjects: Allergenicity; Allergens - administration & dosage; Allergens - immunology; Allergies; Allergy; Anacardiaceae - immunology; Anaphylaxis; Animals; Binding; Buchanania; Buchanania lanzan; Chymases - blood; Cytokines; Cytokines - blood; Female; Flowers & plants; Food Hypersensitivity - immunology; Food Hypersensitivity - pathology; GATA-3 protein; Histamine; Humans; Immunoblotting; Immunoglobulin E; Immunoglobulin E - blood; Immunoglobulin G; Immunoglobulin G - blood; Infiltration; Intestines - drug effects; Intestines - immunology; Intestines - pathology; Lung - drug effects; Lung - immunology; Lung - pathology; Lymphocytes T; Mice; Mice, Inbred BALB C; Molecular weight; Nuts; Nuts - immunology; Organs; PGD2; Plant Extracts - administration & dosage; Plant Extracts - immunology; Plant Proteins - administration & dosage; Plant Proteins - immunology; Prostaglandin D2 - blood; Proteins; Skin Tests; Spleen - drug effects; Spleen - immunology; Spleen - pathology; Transcription factors; Tree nuts; India; PGD2; Allergy; Histamine; Cytokines; Tree nuts; Buchanania lanzan; PGD

Tree nuts are among “Big Eight” and have been reported globally for causing allergy. Buchanania lanzan (Bl) is one of the major tree nuts consumed by Indian population. However, very little is known about B. lanzan's induced allergic manifestation. Therefore, evaluation of it's allergenic...