Combined immunotherapy with controlled interleukin-12 gene therapy and immune checkpoint blockade in recurrent glioblastoma: An open-label, multi-institutional phase I trial - Chiocca, E Antonio; Gelb, Arnold B; Chen, Clark C; Rao, Ganesh; Reardon, David A; Wen, Patrick Y; Bi, Wenya Linda; Peruzzi, Pierpaolo; Amidei, Christina; Triggs, Dan; Seften, Leah; Park, Grace; et al. (Neuro-oncology (Charlottesville, Va.), 2022)
Keywords: Antineoplastic Agents, Immunological - therapeutic use; Antineoplastic Combined Chemotherapy Protocols - pharmacology; Clinical Investigations; Genetic Therapy; Glioblastoma - drug therapy; Glioblastoma - therapy; Humans; Immune Checkpoint Inhibitors; Immunotherapy; Interleukin-12 - genetics; Nivolumab - therapeutic use; clinical trial; gene therapy; glioblastoma; controlled gene expression; immunotherapy