Highly Coordinated Gene Regulation in Mouse Skeletal Muscle Regeneration
Mammalian skeletal muscles are capable of regeneration after injury. Quiescent satellite cells are activated to reenter the cell cycle and to differentiate for repair, recapitulating features of myogenesis during embryonic development. To understand better the molecular mechanism involved in this pr...
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Published in | The Journal of biological chemistry Vol. 278; no. 10; pp. 8826 - 8836 |
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Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
American Society for Biochemistry and Molecular Biology
07.03.2003
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Subjects | |
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Abstract | Mammalian skeletal muscles are capable of regeneration after injury. Quiescent satellite cells are activated to reenter the
cell cycle and to differentiate for repair, recapitulating features of myogenesis during embryonic development. To understand
better the molecular mechanism involved in this process in vivo , we employed high density cDNA microarrays for gene expression profiling in mouse tibialis anterior muscles after a cardiotoxin
injection. Among 16,267 gene elements surveyed, 3,532 elements showed at least a 2.5-fold change at one or more time points
during a 14-day time course. Hierarchical cluster analysis and semiquantitative reverse transcription-PCR showed induction
of genes important for cell cycle control and DNA replication during the early phase of muscle regeneration. Subsequently,
genes for myogenic regulatory factors, a group of imprinted genes and genes with functions to inhibit cell cycle progression
and promote myogenic differentiation, were induced when myogenic stem cells started to differentiate. Induction of a majority
of these genes, including E2f1 and E2f2, was abolished in muscles lacking satellite cell activity after gamma radiation. Regeneration
was severely compromised in E2f1 null mice but not affected in E2f2 null mice. This study identifies novel genes potentially
important for muscle regeneration and reveals highly coordinated myogenic cell proliferation and differentiation programs
in adult skeletal muscle regeneration in vivo . |
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AbstractList | Mammalian skeletal muscles are capable of regeneration after injury. Quiescent satellite cells are activated to reenter the cell cycle and to differentiate for repair, recapitulating features of myogenesis during embryonic development. To understand better the molecular mechanism involved in this process in vivo, we employed high density cDNA microarrays for gene expression profiling in mouse tibialis anterior muscles after a cardiotoxin injection. Among 16,267 gene elements surveyed, 3,532 elements showed at least a 2.5-fold change at one or more time points during a 14-day time course. Hierarchical cluster analysis and semiquantitative reverse transcription-PCR showed induction of genes important for cell cycle control and DNA replication during the early phase of muscle regeneration. Subsequently, genes for myogenic regulatory factors, a group of imprinted genes and genes with functions to inhibit cell cycle progression and promote myogenic differentiation, were induced when myogenic stem cells started to differentiate. Induction of a majority of these genes, including E2f1 and E2f2, was abolished in muscles lacking satellite cell activity after gamma radiation. Regeneration was severely compromised in E2f1 null mice but not affected in E2f2 null mice. This study identifies novel genes potentially important for muscle regeneration and reveals highly coordinated myogenic cell proliferation and differentiation programs in adult skeletal muscle regeneration in vivo. Mammalian skeletal muscles are capable of regeneration after injury. Quiescent satellite cells are activated to reenter the cell cycle and to differentiate for repair, recapitulating features of myogenesis during embryonic development. To understand better the molecular mechanism involved in this process in vivo , we employed high density cDNA microarrays for gene expression profiling in mouse tibialis anterior muscles after a cardiotoxin injection. Among 16,267 gene elements surveyed, 3,532 elements showed at least a 2.5-fold change at one or more time points during a 14-day time course. Hierarchical cluster analysis and semiquantitative reverse transcription-PCR showed induction of genes important for cell cycle control and DNA replication during the early phase of muscle regeneration. Subsequently, genes for myogenic regulatory factors, a group of imprinted genes and genes with functions to inhibit cell cycle progression and promote myogenic differentiation, were induced when myogenic stem cells started to differentiate. Induction of a majority of these genes, including E2f1 and E2f2, was abolished in muscles lacking satellite cell activity after gamma radiation. Regeneration was severely compromised in E2f1 null mice but not affected in E2f2 null mice. This study identifies novel genes potentially important for muscle regeneration and reveals highly coordinated myogenic cell proliferation and differentiation programs in adult skeletal muscle regeneration in vivo . |
Author | Ling Lin Jeoffrey J. Schageman Zhen Yan Sun Young Lee Sangdun Choi Mei Zhang Rebecca Hart R. Sanders Williams Xuebin Liu Frederick A. Thurmond |
Author_xml | – sequence: 1 givenname: Zhen surname: Yan fullname: Yan, Zhen email: zhen.yan@duke.edu organization: Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA. zhen.yan@duke.edu – sequence: 2 givenname: Sangdun surname: Choi fullname: Choi, Sangdun – sequence: 3 givenname: Xuebin surname: Liu fullname: Liu, Xuebin – sequence: 4 givenname: Mei surname: Zhang fullname: Zhang, Mei – sequence: 5 givenname: Jeoffrey J surname: Schageman fullname: Schageman, Jeoffrey J – sequence: 6 givenname: Sun Young surname: Lee fullname: Lee, Sun Young – sequence: 7 givenname: Rebecca surname: Hart fullname: Hart, Rebecca – sequence: 8 givenname: Ling surname: Lin fullname: Lin, Ling – sequence: 9 givenname: Frederick A surname: Thurmond fullname: Thurmond, Frederick A – sequence: 10 givenname: R Sanders surname: Williams fullname: Williams, R Sanders |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/12477723$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1007/s00125-002-0901-y 10.1007/BF00952962 10.1128/MCB.16.12.6977 10.1016/0092-8674(92)90507-9 10.1006/dbio.1997.8721 10.1101/gad.4.8.1450 10.1016/S0959-437X(98)80058-0 10.1073/pnas.87.20.7988 10.1006/dbio.2000.9682 10.1242/dev.125.22.4565 10.1126/science.286.5439.481 10.1038/sj.bjc.6690165 10.1126/science.7863328 10.1074/jbc.M011491200 10.1242/jcs.112.17.2895 10.1093/emboj/18.24.6867 10.1128/MCB.18.4.2334 10.1242/dev.120.4.785 10.1128/MCB.15.8.4215 10.1038/382511a0 10.1074/jbc.M907412199 10.1073/pnas.89.20.9910 10.1002/(SICI)1097-0185(199702)247:2<179::AID-AR4>3.0.CO;2-T 10.1002/aja.1002020304 10.1016/0092-8674(92)90508-A 10.1152/physiolgenomics.00028.2002 10.1128/MCB.17.9.5227 10.1073/pnas.95.3.1091 10.1016/0092-8674(87)90585-X 10.1128/MCB.19.11.7621 10.2337/diabetes.51.6.1913 10.1007/BF00229797 10.1002/(SICI)1097-4652(199610)169:1<23::AID-JCP3>3.0.CO;2-G 10.1016/S0092-8674(00)00066-0 10.1038/364501a0 10.1006/dbio.1996.0172 10.1073/pnas.100501197 10.1073/pnas.96.6.2907 10.1101/gad.7.3.331 10.1016/0168-9525(96)10025-1 10.1016/0092-8674(93)90136-E 10.1096/fj.01-0792fje 10.1101/gad.12.14.2120 10.1101/gad.9.11.1388 10.1006/dbio.2001.0193 10.1016/0092-8674(95)90139-6 10.1101/gad.3.12b.2050 10.1152/ajpcell.2001.280.4.C763 10.1101/gad.12.15.2245 10.1073/pnas.95.7.3603 10.1074/jbc.M009392200 10.1152/jappl.1992.73.6.2538 10.1083/jcb.151.6.1221 10.1101/gad.10.10.1173 10.1096/fj.01-0544fje 10.1002/j.1460-2075.1989.tb03429.x 10.1002/eji.1830090410 10.1139/o98-007 10.1101/gad.13.2.213 10.1016/S0736-5748(02)00041-2 10.1093/brain/85.1.109 10.1111/j.1768-322X.1988.tb00719.x 10.1073/pnas.95.25.14863 |
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References | Grounds (10.1074/jbc.M209879200_bib4) 1993; 3 Stewart (10.1074/jbc.M209879200_bib55) 1996; 169 Braun (10.1074/jbc.M209879200_bib26) 1989; 8 Urashima (10.1074/jbc.M209879200_bib65) 1999; 79 Leone (10.1074/jbc.M209879200_bib14) 1998; 12 Haslett (10.1074/jbc.M209879200_bib50) 2002; 20 Couteaux (10.1074/jbc.M209879200_bib45) 1988; 62 Reynaud (10.1074/jbc.M209879200_bib63) 2000; 275 Williams (10.1074/jbc.M209879200_bib23) 1994; 120 Cossu (10.1074/jbc.M209879200_bib58) 1996; 12 Neuman (10.1074/jbc.M209879200_bib69) 1994; 14 Choi (10.1074/jbc.M209879200_bib38) 1990; 87 Hasty (10.1074/jbc.M209879200_bib18) 1993; 364 Relaix (10.1074/jbc.M209879200_bib53) 1996; 177 Kowalik (10.1074/jbc.M209879200_bib71) 1998; 9 Davis (10.1074/jbc.M209879200_bib25) 1987; 51 Carson (10.1074/jbc.M209879200_bib48) 2002; 16 Pearson (10.1074/jbc.M209879200_bib2) 1962; 85 Leibovitch (10.1074/jbc.M209879200_bib54) 1995; 10 El Kharroubi (10.1074/jbc.M209879200_bib33) 2001; 276 Ewen (10.1074/jbc.M209879200_bib11) 1993; 73 Beauchamp (10.1074/jbc.M209879200_bib61) 2000; 151 Zhang (10.1074/jbc.M209879200_bib41) 1999; 13 Pearce (10.1074/jbc.M209879200_bib1) 1962; 83 Megeney (10.1074/jbc.M209879200_bib44) 1996; 10 Wolffe (10.1074/jbc.M209879200_bib56) 1999; 286 Tamayo (10.1074/jbc.M209879200_bib32) 1999; 96 Roth (10.1074/jbc.M209879200_bib51) 2002; 10 Eisen (10.1074/jbc.M209879200_bib42) 1998; 95 Zhang (10.1074/jbc.M209879200_bib19) 1995; 9 Reynaud (10.1074/jbc.M209879200_bib64) 1999; 19 Hirsch (10.1074/jbc.M209879200_bib37) 1983; 18 Rosenblatt (10.1074/jbc.M209879200_bib39) 1992; 73 Cossu (10.1074/jbc.M209879200_bib57) 1999; 18 Molkentin (10.1074/jbc.M209879200_bib30) 1995; 83 Phelps (10.1074/jbc.M209879200_bib66) 1998; 18 Cserjesi (10.1074/jbc.M209879200_bib29) 1991; 11 Garry (10.1074/jbc.M209879200_bib22) 2000; 97 Lin (10.1074/jbc.M209879200_bib20) 1998; 125 Ohtani (10.1074/jbc.M209879200_bib70) 1996; 16 Kato (10.1074/jbc.M209879200_bib10) 1993; 7 DeGregori (10.1074/jbc.M209879200_bib68) 1995; 15 Yan (10.1074/jbc.M209879200_bib40) 1998; 95 Braun (10.1074/jbc.M209879200_bib16) 1992; 71 Sears (10.1074/jbc.M209879200_bib12) 1997; 17 Skapek (10.1074/jbc.M209879200_bib67) 1995; 267 Ridgeway (10.1074/jbc.M209879200_bib24) 2001; 276 Nevins (10.1074/jbc.M209879200_bib6) 1998; 9 Cornelison (10.1074/jbc.M209879200_bib62) 1997; 191 Galaktionov (10.1074/jbc.M209879200_bib13) 1996; 382 Rhodes (10.1074/jbc.M209879200_bib28) 1989; 3 Rudnicki (10.1074/jbc.M209879200_bib17) 1992; 71 Wittwer (10.1074/jbc.M209879200_bib47) 2002; 16 Edmondson (10.1074/jbc.M209879200_bib27) 1990; 4 Olson (10.1074/jbc.M209879200_bib15) 1991; 104 Koishi (10.1074/jbc.M209879200_bib34) 1995; 202 Seale (10.1074/jbc.M209879200_bib21) 2000; 102 Helin (10.1074/jbc.M209879200_bib43) 1998; 8 Cheng (10.1074/jbc.M209879200_bib9) 1998; 95 Bischoff (10.1074/jbc.M209879200_bib3) 1994 Campbell (10.1074/jbc.M209879200_bib46) 2001; 280 Sreekumar (10.1074/jbc.M209879200_bib49) 2002; 51 Yang (10.1074/jbc.M209879200_bib52) 2002; 45 Won (10.1074/jbc.M209879200_bib8) 1992; 89 Cornelison (10.1074/jbc.M209879200_bib60) 2000; 224 Cooper (10.1074/jbc.M209879200_bib35) 1999; 112 Coutelle (10.1074/jbc.M209879200_bib59) 2001; 236 Springer (10.1074/jbc.M209879200_bib36) 1979; 9 Dyson (10.1074/jbc.M209879200_bib7) 1998; 12 Anderson (10.1074/jbc.M209879200_bib5) 1998; 76 Phelan (10.1074/jbc.M209879200_bib31) 1997; 247 |
References_xml | – start-page: 97 year: 1994 ident: 10.1074/jbc.M209879200_bib3 contributor: fullname: Bischoff – volume: 45 start-page: 1584 year: 2002 ident: 10.1074/jbc.M209879200_bib52 publication-title: Diabetologia doi: 10.1007/s00125-002-0901-y contributor: fullname: Yang – volume: 9 start-page: 585 year: 1998 ident: 10.1074/jbc.M209879200_bib6 publication-title: Cell Growth Differ. contributor: fullname: Nevins – volume: 18 start-page: 229 year: 1983 ident: 10.1074/jbc.M209879200_bib37 publication-title: Immunogenetics doi: 10.1007/BF00952962 contributor: fullname: Hirsch – volume: 16 start-page: 6977 year: 1996 ident: 10.1074/jbc.M209879200_bib70 publication-title: Mol. Cell. Biol. doi: 10.1128/MCB.16.12.6977 contributor: fullname: Ohtani – volume: 71 start-page: 369 year: 1992 ident: 10.1074/jbc.M209879200_bib16 publication-title: Cell doi: 10.1016/0092-8674(92)90507-9 contributor: fullname: Braun – volume: 191 start-page: 270 year: 1997 ident: 10.1074/jbc.M209879200_bib62 publication-title: Dev. Biol. doi: 10.1006/dbio.1997.8721 contributor: fullname: Cornelison – volume: 4 start-page: 1450 year: 1990 ident: 10.1074/jbc.M209879200_bib27 publication-title: Genes Dev. doi: 10.1101/gad.4.8.1450 contributor: fullname: Edmondson – volume: 8 start-page: 28 year: 1998 ident: 10.1074/jbc.M209879200_bib43 publication-title: Curr. Opin. Genet. Dev. doi: 10.1016/S0959-437X(98)80058-0 contributor: fullname: Helin – volume: 87 start-page: 7988 year: 1990 ident: 10.1074/jbc.M209879200_bib38 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.87.20.7988 contributor: fullname: Choi – volume: 224 start-page: 122 year: 2000 ident: 10.1074/jbc.M209879200_bib60 publication-title: Dev. Biol. doi: 10.1006/dbio.2000.9682 contributor: fullname: Cornelison – volume: 9 start-page: 113 year: 1998 ident: 10.1074/jbc.M209879200_bib71 publication-title: Cell Growth Differ. contributor: fullname: Kowalik – volume: 125 start-page: 4565 year: 1998 ident: 10.1074/jbc.M209879200_bib20 publication-title: Development doi: 10.1242/dev.125.22.4565 contributor: fullname: Lin – volume: 286 start-page: 481 year: 1999 ident: 10.1074/jbc.M209879200_bib56 publication-title: Science doi: 10.1126/science.286.5439.481 contributor: fullname: Wolffe – volume: 79 start-page: 1032 year: 1999 ident: 10.1074/jbc.M209879200_bib65 publication-title: Br. J. Cancer doi: 10.1038/sj.bjc.6690165 contributor: fullname: Urashima – volume: 11 start-page: 4854 year: 1991 ident: 10.1074/jbc.M209879200_bib29 publication-title: Mol. Cell. Biol. contributor: fullname: Cserjesi – volume: 267 start-page: 1022 year: 1995 ident: 10.1074/jbc.M209879200_bib67 publication-title: Science doi: 10.1126/science.7863328 contributor: fullname: Skapek – volume: 276 start-page: 19033 year: 2001 ident: 10.1074/jbc.M209879200_bib24 publication-title: J. Biol. Chem. doi: 10.1074/jbc.M011491200 contributor: fullname: Ridgeway – volume: 112 start-page: 2895 year: 1999 ident: 10.1074/jbc.M209879200_bib35 publication-title: J. Cell Sci. doi: 10.1242/jcs.112.17.2895 contributor: fullname: Cooper – volume: 18 start-page: 6867 year: 1999 ident: 10.1074/jbc.M209879200_bib57 publication-title: EMBO J. doi: 10.1093/emboj/18.24.6867 contributor: fullname: Cossu – volume: 18 start-page: 2334 year: 1998 ident: 10.1074/jbc.M209879200_bib66 publication-title: Mol. Cell. Biol. doi: 10.1128/MCB.18.4.2334 contributor: fullname: Phelps – volume: 120 start-page: 785 year: 1994 ident: 10.1074/jbc.M209879200_bib23 publication-title: Development doi: 10.1242/dev.120.4.785 contributor: fullname: Williams – volume: 15 start-page: 4215 year: 1995 ident: 10.1074/jbc.M209879200_bib68 publication-title: Mol. Cell. Biol. doi: 10.1128/MCB.15.8.4215 contributor: fullname: DeGregori – volume: 382 start-page: 511 year: 1996 ident: 10.1074/jbc.M209879200_bib13 publication-title: Nature doi: 10.1038/382511a0 contributor: fullname: Galaktionov – volume: 275 start-page: 18767 year: 2000 ident: 10.1074/jbc.M209879200_bib63 publication-title: J. Biol. Chem. doi: 10.1074/jbc.M907412199 contributor: fullname: Reynaud – volume: 89 start-page: 9910 year: 1992 ident: 10.1074/jbc.M209879200_bib8 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.89.20.9910 contributor: fullname: Won – volume: 83 start-page: 535 year: 1962 ident: 10.1074/jbc.M209879200_bib1 publication-title: J. Neurol. Bacteriol. contributor: fullname: Pearce – volume: 247 start-page: 179 year: 1997 ident: 10.1074/jbc.M209879200_bib31 publication-title: Anat. Rec. doi: 10.1002/(SICI)1097-0185(199702)247:2<179::AID-AR4>3.0.CO;2-T contributor: fullname: Phelan – volume: 202 start-page: 244 year: 1995 ident: 10.1074/jbc.M209879200_bib34 publication-title: Dev. Dyn. doi: 10.1002/aja.1002020304 contributor: fullname: Koishi – volume: 71 start-page: 383 year: 1992 ident: 10.1074/jbc.M209879200_bib17 publication-title: Cell doi: 10.1016/0092-8674(92)90508-A contributor: fullname: Rudnicki – volume: 10 start-page: 181 year: 2002 ident: 10.1074/jbc.M209879200_bib51 publication-title: Physiol. Genomics doi: 10.1152/physiolgenomics.00028.2002 contributor: fullname: Roth – volume: 14 start-page: 6607 year: 1994 ident: 10.1074/jbc.M209879200_bib69 publication-title: Mol. Cell. Biol. contributor: fullname: Neuman – volume: 17 start-page: 5227 year: 1997 ident: 10.1074/jbc.M209879200_bib12 publication-title: Mol. Cell. Biol. doi: 10.1128/MCB.17.9.5227 contributor: fullname: Sears – volume: 95 start-page: 1091 year: 1998 ident: 10.1074/jbc.M209879200_bib9 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.95.3.1091 contributor: fullname: Cheng – volume: 51 start-page: 987 year: 1987 ident: 10.1074/jbc.M209879200_bib25 publication-title: Cell doi: 10.1016/0092-8674(87)90585-X contributor: fullname: Davis – volume: 19 start-page: 7621 year: 1999 ident: 10.1074/jbc.M209879200_bib64 publication-title: Mol. Cell. Biol. doi: 10.1128/MCB.19.11.7621 contributor: fullname: Reynaud – volume: 51 start-page: 1913 year: 2002 ident: 10.1074/jbc.M209879200_bib49 publication-title: Diabetes doi: 10.2337/diabetes.51.6.1913 contributor: fullname: Sreekumar – volume: 104 start-page: 7 year: 1991 ident: 10.1074/jbc.M209879200_bib15 publication-title: Mol. Cell. Biochem. doi: 10.1007/BF00229797 contributor: fullname: Olson – volume: 169 start-page: 23 year: 1996 ident: 10.1074/jbc.M209879200_bib55 publication-title: J. Cell. Physiol. doi: 10.1002/(SICI)1097-4652(199610)169:1<23::AID-JCP3>3.0.CO;2-G contributor: fullname: Stewart – volume: 102 start-page: 777 year: 2000 ident: 10.1074/jbc.M209879200_bib21 publication-title: Cell doi: 10.1016/S0092-8674(00)00066-0 contributor: fullname: Seale – volume: 364 start-page: 501 year: 1993 ident: 10.1074/jbc.M209879200_bib18 publication-title: Nature doi: 10.1038/364501a0 contributor: fullname: Hasty – volume: 177 start-page: 383 year: 1996 ident: 10.1074/jbc.M209879200_bib53 publication-title: Dev. Biol. doi: 10.1006/dbio.1996.0172 contributor: fullname: Relaix – volume: 97 start-page: 5416 year: 2000 ident: 10.1074/jbc.M209879200_bib22 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.100501197 contributor: fullname: Garry – volume: 96 start-page: 2907 year: 1999 ident: 10.1074/jbc.M209879200_bib32 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.96.6.2907 contributor: fullname: Tamayo – volume: 7 start-page: 331 year: 1993 ident: 10.1074/jbc.M209879200_bib10 publication-title: Genes Dev. doi: 10.1101/gad.7.3.331 contributor: fullname: Kato – volume: 12 start-page: 218 year: 1996 ident: 10.1074/jbc.M209879200_bib58 publication-title: Trends Genet. doi: 10.1016/0168-9525(96)10025-1 contributor: fullname: Cossu – volume: 73 start-page: 487 year: 1993 ident: 10.1074/jbc.M209879200_bib11 publication-title: Cell doi: 10.1016/0092-8674(93)90136-E contributor: fullname: Ewen – volume: 3 start-page: 210 year: 1993 ident: 10.1074/jbc.M209879200_bib4 publication-title: Mol. Cell. Biol. Hum. Dis. Ser. contributor: fullname: Grounds – volume: 16 start-page: 884 year: 2002 ident: 10.1074/jbc.M209879200_bib47 publication-title: FASEB J. doi: 10.1096/fj.01-0792fje contributor: fullname: Wittwer – volume: 12 start-page: 2120 year: 1998 ident: 10.1074/jbc.M209879200_bib14 publication-title: Genes Dev. doi: 10.1101/gad.12.14.2120 contributor: fullname: Leone – volume: 9 start-page: 1388 year: 1995 ident: 10.1074/jbc.M209879200_bib19 publication-title: Genes Dev. doi: 10.1101/gad.9.11.1388 contributor: fullname: Zhang – volume: 236 start-page: 136 year: 2001 ident: 10.1074/jbc.M209879200_bib59 publication-title: Dev. Biol. doi: 10.1006/dbio.2001.0193 contributor: fullname: Coutelle – volume: 83 start-page: 1125 year: 1995 ident: 10.1074/jbc.M209879200_bib30 publication-title: Cell doi: 10.1016/0092-8674(95)90139-6 contributor: fullname: Molkentin – volume: 3 start-page: 2050 year: 1989 ident: 10.1074/jbc.M209879200_bib28 publication-title: Genes Dev. doi: 10.1101/gad.3.12b.2050 contributor: fullname: Rhodes – volume: 280 start-page: C763 year: 2001 ident: 10.1074/jbc.M209879200_bib46 publication-title: Am. J. Physiol. doi: 10.1152/ajpcell.2001.280.4.C763 contributor: fullname: Campbell – volume: 12 start-page: 2245 year: 1998 ident: 10.1074/jbc.M209879200_bib7 publication-title: Genes Dev. doi: 10.1101/gad.12.15.2245 contributor: fullname: Dyson – volume: 95 start-page: 3603 year: 1998 ident: 10.1074/jbc.M209879200_bib40 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.95.7.3603 contributor: fullname: Yan – volume: 276 start-page: 8674 year: 2001 ident: 10.1074/jbc.M209879200_bib33 publication-title: J. Biol. Chem. doi: 10.1074/jbc.M009392200 contributor: fullname: El Kharroubi – volume: 73 start-page: 2538 year: 1992 ident: 10.1074/jbc.M209879200_bib39 publication-title: J. Appl. Physiol. doi: 10.1152/jappl.1992.73.6.2538 contributor: fullname: Rosenblatt – volume: 151 start-page: 1221 year: 2000 ident: 10.1074/jbc.M209879200_bib61 publication-title: J. Cell Biol. doi: 10.1083/jcb.151.6.1221 contributor: fullname: Beauchamp – volume: 10 start-page: 1173 year: 1996 ident: 10.1074/jbc.M209879200_bib44 publication-title: Genes Dev. doi: 10.1101/gad.10.10.1173 contributor: fullname: Megeney – volume: 10 start-page: 251 year: 1995 ident: 10.1074/jbc.M209879200_bib54 publication-title: Oncogene contributor: fullname: Leibovitch – volume: 16 start-page: 207 year: 2002 ident: 10.1074/jbc.M209879200_bib48 publication-title: FASEB J. doi: 10.1096/fj.01-0544fje contributor: fullname: Carson – volume: 8 start-page: 701 year: 1989 ident: 10.1074/jbc.M209879200_bib26 publication-title: EMBO J. doi: 10.1002/j.1460-2075.1989.tb03429.x contributor: fullname: Braun – volume: 9 start-page: 301 year: 1979 ident: 10.1074/jbc.M209879200_bib36 publication-title: Eur. J. Immunol. doi: 10.1002/eji.1830090410 contributor: fullname: Springer – volume: 76 start-page: 13 year: 1998 ident: 10.1074/jbc.M209879200_bib5 publication-title: Biochem. Cell Biol. doi: 10.1139/o98-007 contributor: fullname: Anderson – volume: 13 start-page: 213 year: 1999 ident: 10.1074/jbc.M209879200_bib41 publication-title: Genes Dev. doi: 10.1101/gad.13.2.213 contributor: fullname: Zhang – volume: 20 start-page: 359 year: 2002 ident: 10.1074/jbc.M209879200_bib50 publication-title: Int. J. Dev. Neurosci. doi: 10.1016/S0736-5748(02)00041-2 contributor: fullname: Haslett – volume: 85 start-page: 109 year: 1962 ident: 10.1074/jbc.M209879200_bib2 publication-title: Brain doi: 10.1093/brain/85.1.109 contributor: fullname: Pearson – volume: 62 start-page: 171 year: 1988 ident: 10.1074/jbc.M209879200_bib45 publication-title: Biol. Cell doi: 10.1111/j.1768-322X.1988.tb00719.x contributor: fullname: Couteaux – volume: 95 start-page: 14863 year: 1998 ident: 10.1074/jbc.M209879200_bib42 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.95.25.14863 contributor: fullname: Eisen |
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Snippet | Mammalian skeletal muscles are capable of regeneration after injury. Quiescent satellite cells are activated to reenter the
cell cycle and to differentiate for... Mammalian skeletal muscles are capable of regeneration after injury. Quiescent satellite cells are activated to reenter the cell cycle and to differentiate for... |
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SubjectTerms | Animals Base Sequence Cell Cycle Proteins Cobra Cardiotoxin Proteins - administration & dosage DNA Primers DNA-Binding Proteins E2F Transcription Factors E2F1 Transcription Factor Fluorescent Antibody Technique, Indirect Gene Expression Profiling Gene Expression Regulation Genes, cdc Male Mice Mice, Inbred C57BL Microscopy, Electron Muscle, Skeletal - metabolism Muscle, Skeletal - physiology Muscle, Skeletal - ultrastructure Oligonucleotide Array Sequence Analysis Regeneration - genetics Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Transcription Factors - genetics |
Title | Highly Coordinated Gene Regulation in Mouse Skeletal Muscle Regeneration |
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