A Global lmmunological Observatory to meet a time of pandemics
SARS-CoV-2 presents an unprecedented international challenge, but it will not be the last such threat. Here, we argue that the world needs to be much better prepared to rapidly detect, define and defeat future pandemics. We propose that a Global Immunological Observatory and associated developments...
Saved in:
| Published in | eLife Vol. 9 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
eLife Sciences Publications Ltd
08.06.2020
eLife Sciences Publications, Ltd |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | SARS-CoV-2 presents an unprecedented international challenge, but it will not be the last such threat. Here, we argue that the world needs to be much better prepared to rapidly detect, define and defeat future pandemics. We propose that a Global Immunological Observatory and associated developments in systems immunology, therapeutics and vaccine design should be at the heart of this enterprise. |
|---|---|
| AbstractList | SARS-CoV-2 presents an unprecedented international challenge, but it will not be the last such threat. Here, we argue that the world needs to be much better prepared to rapidly detect, define and defeat future pandemics. We propose that a Global Immunological Observatory and associated developments in systems immunology, therapeutics and vaccine design should be at the heart of this enterprise. SARS-CoV-2 presents an unprecedented international challenge, but it will not be the last such threat. Here, we argue that the world needs to be much better prepared to rapidly detect, define and defeat future pandemics. We propose that a Global Immunological Observatory and associated developments in systems immunology, therapeutics and vaccine design should be at the heart of this enterprise.SARS-CoV-2 presents an unprecedented international challenge, but it will not be the last such threat. Here, we argue that the world needs to be much better prepared to rapidly detect, define and defeat future pandemics. We propose that a Global Immunological Observatory and associated developments in systems immunology, therapeutics and vaccine design should be at the heart of this enterprise. |
| Author | Douek, Daniel C Metcalf, C Jessica E Farrar, Jeremy McDermott, Adrian B Mina, Michael J Grenfell, Bryan T |
| Author_xml | – sequence: 1 givenname: Michael J orcidid: 0000-0002-0674-5762 surname: Mina fullname: Mina, Michael J organization: Center for Communicable Disease Dynamics, Department of Epidemiology, and Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, United States, Department of Pathology, Brigham and Women’s Hospital, Boston, United States – sequence: 2 givenname: C Jessica E orcidid: 0000-0003-3166-7521 surname: Metcalf fullname: Metcalf, C Jessica E organization: Department of Ecology and Evolutionary Biology, Princeton University, Princeton, United States, Woodrow Wilson School, Princeton University, Princeton, United States – sequence: 3 givenname: Adrian B orcidid: 0000-0003-0616-9117 surname: McDermott fullname: McDermott, Adrian B organization: Vaccine Research Center, National Institutes of Health, Bethesda, United States – sequence: 4 givenname: Daniel C surname: Douek fullname: Douek, Daniel C organization: Vaccine Research Center, National Institutes of Health, Bethesda, United States – sequence: 5 givenname: Jeremy surname: Farrar fullname: Farrar, Jeremy organization: The Wellcome Trust, London, United Kingdom – sequence: 6 givenname: Bryan T orcidid: 0000-0003-3227-5909 surname: Grenfell fullname: Grenfell, Bryan T organization: Department of Ecology and Evolutionary Biology, Princeton University, Princeton, United States, Woodrow Wilson School, Princeton University, Princeton, United States, Fogarty International Center, National Institutes of Health, Bethesda, United States |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32510329$$D View this record in MEDLINE/PubMed |
| BookMark | eNptks1rHCEYxqWkNGmaU-9loJdC2VRndNRLIIQ2DSzk0kJv8uq8bl2ccauzgfz3dXfTkIR68evn46Pv85YcTWlCQt4zei6F4F9wGTyeC6WVfkVOWirogir-6-jJ-JiclbKmtUmuFNNvyHHXCka7Vp-Qi8vmOiYLsYnjuJ1STKvg6uzWFsx3MKd838ypGRHnBpo5jNgk32xgGnAMrrwjrz3EgmcP_Sn5-e3rj6vvi-Xt9c3V5XLhOk31wtreq4FVm5xbpoWlQrC-194D8I5x1VY3AIPSQ685Dowi46A6bmkPtMPulNwcdIcEa7PJYYR8bxIEs19IeWUgz8FFNI6BlVx46png9SbbK0u9djhIxxTstC4OWputHXFwOM0Z4jPR5ztT-G1W6c7IVrc976vApweBnP5sscxmDMVhjDBh2hbTckYllVKqin58ga7TNk_1q3ZUrVrXdbJSH546erTyr0wV-HwAXE6lZPSPCKNmlwOzz4HZ56DS7AXtwgxzSLvnhPjfM38BIZO02g |
| CitedBy_id | crossref_primary_10_1016_j_epidem_2024_100806 crossref_primary_10_1016_j_epidem_2024_100808 crossref_primary_10_1073_pnas_2013182117 crossref_primary_10_3390_pathogens11070732 crossref_primary_10_7554_eLife_78233 crossref_primary_10_3389_fpubh_2024_1408193 crossref_primary_10_1126_sciadv_abl4183 crossref_primary_10_1146_annurev_pathmechdis_031521_042754 crossref_primary_10_1093_ofid_ofab178 crossref_primary_10_1098_rstb_2020_0358 crossref_primary_10_1371_journal_pcbi_1010893 crossref_primary_10_1016_j_epidem_2022_100645 crossref_primary_10_1126_scitranslmed_abd2400 crossref_primary_10_1016_j_it_2020_06_011 crossref_primary_10_3390_ijerph18031030 crossref_primary_10_1371_journal_pntd_0010657 crossref_primary_10_1126_science_adq0072 crossref_primary_10_1038_s41579_024_01064_8 crossref_primary_10_1038_s41586_022_05200_3 crossref_primary_10_1016_S2542_5196_21_00031_0 crossref_primary_10_1038_s41591_021_01234_8 crossref_primary_10_1126_science_abd7343 crossref_primary_10_1371_journal_pmed_1004107 crossref_primary_10_1098_rsif_2023_0247 crossref_primary_10_1016_j_it_2021_07_001 crossref_primary_10_1093_infdis_jiab446 crossref_primary_10_1126_sciimmunol_abe9950 crossref_primary_10_1371_journal_pgph_0001568 crossref_primary_10_1038_s41467_023_44199_7 crossref_primary_10_1371_journal_pcbi_1012211 crossref_primary_10_1073_pnas_2208895119 crossref_primary_10_1038_d41586_022_01474_9 crossref_primary_10_1016_S1473_3099_24_00585_1 crossref_primary_10_1111_sji_13125 crossref_primary_10_1016_j_epidem_2021_100516 crossref_primary_10_1016_j_lmd_2024_100032 crossref_primary_10_1016_S1473_3099_22_00664_8 crossref_primary_10_1029_2024GH001193 crossref_primary_10_1038_s41598_024_64624_1 crossref_primary_10_1126_science_abh0635 crossref_primary_10_1016_S2666_5247_21_00312_8 crossref_primary_10_1371_journal_pone_0258516 crossref_primary_10_1016_S0140_6736_22_01277_6 crossref_primary_10_1038_s41467_021_23651_6 crossref_primary_10_1093_ije_dyae160 crossref_primary_10_1038_s41559_024_02594_3 crossref_primary_10_1016_j_epidem_2024_100776 crossref_primary_10_1126_science_abn9410 crossref_primary_10_1016_S0140_6736_22_00629_8 |
| Cites_doi | 10.1126/science.aap7463 10.1016/S0140-6736(17)30054-5 10.1016/S0140-6736(16)30164-7 10.1016/j.tim.2017.09.004 10.1101/2020.03.24.006544 10.1126/science.1090727 10.1016/j.bsheal.2020.01.003 10.1126/science.aaa0698 10.1016/j.cell.2019.07.009 |
| ContentType | Journal Article |
| Copyright | 2020. This work is published under http://creativecommons.org/publicdomain/zero/1.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| Copyright_xml | – notice: 2020. This work is published under http://creativecommons.org/publicdomain/zero/1.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7X7 7XB 88E 88I 8FE 8FH 8FI 8FJ 8FK ABUWG AFKRA AZQEC BBNVY BENPR BHPHI CCPQU COVID DWQXO FYUFA GHDGH GNUQQ HCIFZ K9. LK8 M0S M1P M2P M7P PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI PRINS Q9U 7X8 5PM DOA |
| DOI | 10.7554/eLife.58989 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Science Database (Alumni Edition) ProQuest SciTech Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials Biological Science Collection ProQuest Central Natural Science Collection ProQuest One Coronavirus Research Database ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) Biological Sciences ProQuest Health & Medical Collection Medical Database Science Database Biological Science Database ProQuest Central Premium ProQuest One Academic (New) Publicly Available Content Database ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest Central Basic MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Publicly Available Content Database ProQuest Central Student ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest One Health & Nursing ProQuest Natural Science Collection ProQuest Central China ProQuest Central ProQuest One Applied & Life Sciences ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) Natural Science Collection ProQuest Central Korea Health & Medical Research Collection Biological Science Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest Science Journals (Alumni Edition) ProQuest Biological Science Collection ProQuest Central Basic ProQuest Science Journals ProQuest One Academic Eastern Edition Coronavirus Research Database ProQuest Hospital Collection Health Research Premium Collection (Alumni) Biological Science Database ProQuest SciTech Collection ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | CrossRef MEDLINE - Academic Publicly Available Content Database MEDLINE |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 4 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Biology Public Health |
| EISSN | 2050-084X |
| ExternalDocumentID | oai_doaj_org_article_c1ab745f0f1545b0b68b0f9ced7c18ae PMC7292646 32510329 10_7554_eLife_58989 |
| Genre | Journal Article |
| GrantInformation_xml | – fundername: NIH HHS grantid: DP5 OD028145 |
| GroupedDBID | 53G 5VS 7X7 88E 88I 8FE 8FH 8FI 8FJ AAFWJ AAKDD AAYXX ABUWG ACGFO ACGOD ACPRK ADBBV ADRAZ AENEX AFKRA AFPKN ALIPV ALMA_UNASSIGNED_HOLDINGS AOIJS AZQEC BAWUL BBNVY BCNDV BENPR BHPHI BPHCQ BVXVI CCPQU CITATION DIK DWQXO EMOBN FYUFA GNUQQ GROUPED_DOAJ GX1 HCIFZ HMCUK HYE IAO IEA IHR INH INR ISR ITC KQ8 LK8 M1P M2P M48 M7P M~E NQS OK1 PGMZT PHGZM PHGZT PIMPY PQQKQ PROAC PSQYO RHI RNS RPM UKHRP 3V. CGR CUY CVF ECM EIF FRP NPM RHF 7XB 8FK COVID K9. PJZUB PKEHL PPXIY PQEST PQGLB PQUKI PRINS Q9U 7X8 5PM PUEGO |
| ID | FETCH-LOGICAL-c3909-bb6f8d158944b195b0551669ffaa431482032aad89d694ed10e14a834b06a03e3 |
| IEDL.DBID | M48 |
| ISSN | 2050-084X |
| IngestDate | Wed Aug 27 01:12:16 EDT 2025 Thu Aug 21 18:41:44 EDT 2025 Thu Jul 10 17:43:26 EDT 2025 Fri Jul 25 11:46:21 EDT 2025 Thu Jan 02 22:59:12 EST 2025 Thu Apr 24 23:00:20 EDT 2025 Tue Jul 01 04:12:48 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Keywords | COVID-19 global health epidemiology SARS-CoV-2 inflammation science forum serology global surveillance pandemic human immunology |
| Language | English |
| License | This is an open-access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c3909-bb6f8d158944b195b0551669ffaa431482032aad89d694ed10e14a834b06a03e3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 These authors contributed equally to this work. |
| ORCID | 0000-0003-3166-7521 0000-0003-3227-5909 0000-0002-0674-5762 0000-0003-0616-9117 |
| OpenAccessLink | http://journals.scholarsportal.info/openUrl.xqy?doi=10.7554/eLife.58989 |
| PMID | 32510329 |
| PQID | 2418983337 |
| PQPubID | 2045579 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_c1ab745f0f1545b0b68b0f9ced7c18ae pubmedcentral_primary_oai_pubmedcentral_nih_gov_7292646 proquest_miscellaneous_2410707778 proquest_journals_2418983337 pubmed_primary_32510329 crossref_primary_10_7554_eLife_58989 crossref_citationtrail_10_7554_eLife_58989 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 20200608 |
| PublicationDateYYYYMMDD | 2020-06-08 |
| PublicationDate_xml | – month: 6 year: 2020 text: 20200608 day: 8 |
| PublicationDecade | 2020 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England – name: Cambridge |
| PublicationTitle | eLife |
| PublicationTitleAlternate | Elife |
| PublicationYear | 2020 |
| Publisher | eLife Sciences Publications Ltd eLife Sciences Publications, Ltd |
| Publisher_xml | – name: eLife Sciences Publications Ltd – name: eLife Sciences Publications, Ltd |
| References | Xu (bib9) 2015; 348 Morris (bib8) 2018; 26 Khan (bib4) 2020 Daszak (bib2) 2020; 2 Carroll (bib1) 2018; 359 Metcalf (bib7) 2017; 389 Metcalf (bib6) 2016; 388 Kula (bib5) 2019; 178 Grenfell (bib3) 2004; 303 |
| References_xml | – volume: 359 start-page: 872 year: 2018 ident: bib1 article-title: The Global Virome Project publication-title: Science doi: 10.1126/science.aap7463 – volume: 389 year: 2017 ident: bib7 article-title: Opportunities and challenges of a World Serum Bank – Authors' reply publication-title: The Lancet doi: 10.1016/S0140-6736(17)30054-5 – volume: 388 start-page: 728 year: 2016 ident: bib6 article-title: Use of serological surveys to generate key insights into the changing global landscape of infectious disease publication-title: The Lancet doi: 10.1016/S0140-6736(16)30164-7 – volume: 26 start-page: 102 year: 2018 ident: bib8 article-title: Predictive modeling of influenza shows the promise of applied evolutionary biology publication-title: Trends in Microbiology doi: 10.1016/j.tim.2017.09.004 – volume-title: bioRxiv year: 2020 ident: bib4 article-title: Analysis of serologic cross-reactivity between common human coronaviruses and SARS-CoV-2 using coronavirus antigen microarray doi: 10.1101/2020.03.24.006544 – volume: 303 start-page: 327 year: 2004 ident: bib3 article-title: Unifying the epidemiological and evolutionary dynamics of pathogens publication-title: Science doi: 10.1126/science.1090727 – volume: 2 start-page: 6 year: 2020 ident: bib2 article-title: A strategy to prevent future epidemics similar to the 2019-nCoV outbreak publication-title: Biosafety and Health doi: 10.1016/j.bsheal.2020.01.003 – volume: 348 year: 2015 ident: bib9 article-title: Comprehensive serological profiling of human populations using a synthetic human virome publication-title: Science doi: 10.1126/science.aaa0698 – volume: 178 start-page: 1016 year: 2019 ident: bib5 article-title: T-Scan: A genome-wide method for the systematic discovery of T cell epitopes publication-title: Cell doi: 10.1016/j.cell.2019.07.009 |
| SSID | ssj0000748819 |
| Score | 2.4803736 |
| Snippet | SARS-CoV-2 presents an unprecedented international challenge, but it will not be the last such threat. Here, we argue that the world needs to be much better... |
| SourceID | doaj pubmedcentral proquest pubmed crossref |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source |
| SubjectTerms | Animals Anti-Infective Agents Antibodies Blood & organ donations Climate Change Cohort Studies Communicable Disease Control - methods Communicable Disease Control - organization & administration Communicable Diseases, Emerging - diagnosis Communicable Diseases, Emerging - epidemiology Communicable Diseases, Emerging - immunology Communicable Diseases, Emerging - prevention & control Coronavirus Infections - epidemiology Coronaviruses COVID-19 Disaster Planning - organization & administration Disease transmission Drug Development Epidemiology Epidemiology and Global Health Forecasting Global Health - trends global surveillance Humans Identification Immunology Immunology and Inflammation Interdisciplinary Communication International Cooperation Mass Screening - organization & administration Models, Animal Observatories pandemic Pandemics Pandemics - prevention & control Pathogens Pneumonia, Viral - epidemiology Population Surveillance - methods Public health SARS-CoV-2 Science Forum Serologic Tests Serology Severe acute respiratory syndrome coronavirus 2 Vaccines Weather Zoonoses |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3NS-UwEA8iCF7Er9XuuhLB00I1MWnTXBZUFBF1Lyt4K5k2wQfaij4P_vfOJH2P90Tw4rUZ6OQ3SWYmH79hbB8EOnXhfK4gQK6VKXKAMuRKOysDOOPi8-jrm_LiVl_eFXczpb7oTliiB07AHTbSgdFFEIGcPQgoKxDBNr41jaycp9UXfd5MMhXXYIMDU9r0IM-gyzz0V6PgDwqqljjngiJT_2fh5cdbkjNu53yVrQzxIj9Oeq6xBd-ts6VUQfJtg_095om1nz_QQ4_JSsb_Qdpt7Z_f-Ljnj96PueNUSJ73gT_RzvHjqHnZZLfnZ_9PL_KhJELeKCtsxLFqJXZDa5AW8aCDrtKG4ByGArqigujOtZVtS6t9K4WX2lVKgyidUF79YItd3_ltxiWgqCK6NE-nr9JhKBY8gNJKYdJUZOzPBKW6GfjCqWzFQ415A0FaR0jrCGnG9qfCT4km43OxE4J7KkLc1vEDWrweLF5_ZfGM7UyMVQ8T7qXGQAR_oJQyGdubNuNUofMP1_n-NcoQuZExVca2km2nmqijSC2IGpo5q8-pOt_Sje4jHTemJxhVlj-_o2-_2PIRJfS0zVPtsMXx86v_jVHPGHbjAH8HYNQBLQ priority: 102 providerName: Directory of Open Access Journals – databaseName: Health & Medical Collection dbid: 7X7 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1La9wwEB7alEKhhDR9OY-iQk4FN1IkW_IlIQkNofRxaWBvRrKldiGxt7ubQ_59ZiSv2y2hV2sO45mR5iHNNwAHjqNT59bn0gWXK6mL3Lky5FLZSgRntY3t0V-_lZdX6vOkmAwFt8XwrHJ1JsaDuu0bqpEfoqcxlZFS6pPZ75ymRtHt6jBC4zE8Iegysmo90WONBd2jQY-X2vI0Os5D_2Ua_MeCZiauOaKI1_9QkPnvW8m_nM_FFmwOUSM7TWp-AY98tw1P0xzJu214nopvLPUUvYTjU5aw_Nk1tX-szjf23aUabD-_Y8ue3Xi_ZJbReHnWBzajevLNtFm8gquLTz_OL_NhUELeyIpXUbqmFfhbSjmUAyqgEGVZhWAtBgjK0Jh0a1tTtWWlfCu4F8oaqRwvLZdevoaNru_8W2DCIakkEDVPd7LCYoAWvHNSSYmpVJHBh5XU6mZAEadhFtc1ZhMk4jqKuI4izuBgJJ4l8IyHyc5I_CMJIV7HD_38Zz1soLoR1mlVBB4o6HPclcbxUDW-1Y0w1mewt1JePWzDRf3HaDJ4Py7jBqJbEdv5_jbSEOSR1iaDN0nXIyfyKAIOIod6zQrWWF1f6aa_Ikg3Ji0Ya5Y7_2drF54dUQJPZR2zBxvL-a3fxyhn6d5FU74H8qT8ew priority: 102 providerName: ProQuest |
| Title | A Global lmmunological Observatory to meet a time of pandemics |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/32510329 https://www.proquest.com/docview/2418983337 https://www.proquest.com/docview/2410707778 https://pubmed.ncbi.nlm.nih.gov/PMC7292646 https://doaj.org/article/c1ab745f0f1545b0b68b0f9ced7c18ae |
| Volume | 9 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV3da9swED_6AaMvY2NfXrugQZ8GzqRKtqyXjXa0lLF2YyyQNyPZUhdI7S5Nof3vdyfbYSnZq3W25dNJ97uT9TuAQ8fRqXPrU-mCS5XUWepcHlKprBHBWW3j8eiLy_x8or5Os-kWDMU4ewXebgztqJ7UZDEf3_95-IwTHvHrWKM3_Oi_zYIfZ1QIcRt20SVpKmVw0eP8uCRrtFNhuvN5j-_ZgyfyKBLLmTXnFDn8NwHPx_9P_uOQzp7B0x5JsuNu6J_Dlm9ewKdj1rH4szkd_BhWNvbdddnXdvHAli279n7JLKPC8qwN7IYyydez6vYlTM5Of305T_sSCWklDTdRr0Ut8DuUcsJkqPpM5LkJwVqEBqqgAunW1oWpc6N8LbgXyhZSOZ5bLr18BTtN2_g3wIRDUUn0aZ52Y4VFaBa8c1JJiUFUlsCHQTdl1fOHUxmLeYlxBOm0jDoto04TOFwJ33S0GZvFTkjJKxHiuo4X2sVV2U-dshLWaZUFHgjuOe7ywvFgKl_rShTWJ3AwDFE52E-JVoAvkFLqBN6vmnHq0H6IbXx7F2WI7EjrIoHX3YiuejJYRAJ6bazXurre0sx-R3puDFcQZeZv__vMfdg7oqidcjnFAewsF3f-HUKbpRvBtp7qEeyenF7--DmKCYJRNOW_bkf6Tg |
| linkProvider | Scholars Portal |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB6VIgQSQlBegQJGKhek0GTtxM4BUHlUW7otl1baW2ondrtSmyy7W6H9U_xGZpwHLKq49RqPotF4xvOwZz6ALROhU4-0DblxJhRcJqExqQu50FnsjJbat0cfHKbDY_FtnIzX4FfXC0PPKrsz0R_UZV1QjXwbPY3KFOdcfpz-CAk1im5XOwiNRi327fInpmzz93tfcH_fDAa7X48-D8MWVSAsML_PPCuqjBOVCWHiLEFukzhNM-e0Rm8qFGGKa12qrEwzYcs4srHQigsTpTriluN_b8BNJI0o2ZNj2dd00B0r9LBNG6BER71tRxNn3yWE0bji-Dw-wFVB7b9vM_9ydrv34V4bpbKdRq0ewJqtNuBWg1u53IC7TbGPNT1MD-HDDmuwA9g5tZt05yn7bpqabz1bskXNLqxdMM0Izp7Vjk2pfn0xKeaP4PhaRPgY1qu6sk-BxQZJOQ1ts3QHHGsMCJ01hgvOMXVLAnjbSS0v2qnlBJ5xnmP2QiLOvYhzL-IAtnriaTOs42qyTyT-noQmbPsP9ew0bw02L2JtpEhc5CjINJFJlYlcVthSFrHSNoDNbvPy1uzn-R8lDeB1v4wGS7cwurL1paehEUtSqgCeNHvdc8IHfsAhcihXtGCF1dWVanLmh4JjkoSxbfrs_2y9gtvDo4NRPto73H8OdwZUPKCSktqE9cXs0r7ACGthXnq1ZnBy3Xb0G1WQN30 |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3db9MwED-NTiAkhGB8BQYYabwghSa1EzsPgDa2amOjTIhJewt2YkOlrSltJ9R_jb-OO-cDiibe9hqfotP5zvdh3_0AtkyETj3SNuTGmVBwmYTGpC7kQmexM1pq3x79cZTun4gPp8npGvxqe2HoWWV7JvqDuqwKqpH30dOoTHHOZd81zyKOd4fvpj9CQpCim9YWTqNWkUO7_Inp2_zNwS7u9cvBYLj35f1-2CAMhAXm-plnS5VxojIhTJwlyHkSp2nmnNboWYUifHGtS5WVaSZsGUc2FlpxYaJUR9xy_O81WJeUFfVgfWdvdPy5q_Cgc1bob-umQIluu2-Pxs6-TgixccUNerSAy0Lcf19q_uX6hnfgdhOzsu1aye7Cmp1swPUaxXK5Abfq0h-rO5ruwdttViMJsDNqPmlPV_bJ1BXgarZki4qdW7tgmhG4Pascm1I1-3xczO_DyZUI8QH0JtXEPgIWGyTlNMLN0o1wrDE8dNYYLjjHRC4J4FUrtbxoZpgTlMZZjrkMiTj3Is69iAPY6oin9eiOy8l2SPwdCc3b9h-q2be8Md-8iLWRInGRo5DTRCZVJnJZYUtZxErbADbbzcubQ2Ce_1HZAF50y2i-dCejJ7a68DQ0cElKFcDDeq87TvjAjztEDuWKFqywuroyGX_3I8IxZcJIN338f7aeww20ofzoYHT4BG4OqJJA9SW1Cb3F7MI-xXBrYZ41es3g61Wb0m8taT0Y |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+Global+lmmunological+Observatory+to+meet+a+time+of+pandemics&rft.jtitle=eLife&rft.au=Mina%2C+Michael+J&rft.au=Metcalf%2C+C+Jessica+E&rft.au=McDermott%2C+Adrian+B&rft.au=Douek%2C+Daniel+C&rft.date=2020-06-08&rft.eissn=2050-084X&rft.volume=9&rft_id=info:doi/10.7554%2FeLife.58989&rft_id=info%3Apmid%2F32510329&rft.externalDocID=32510329 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2050-084X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2050-084X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2050-084X&client=summon |