A recombinant protein containing influenza viral conserved epitopes and superantigen induces broad-spectrum protection - Li, Yansheng; Xu, Mingkai; Li, Yongqiang; Gu, Wu; Halimu, Gulinare; Li, Yuqi; Zhang, Zhichun; Zhou, Libao; Liao, Hui; Yao, Songyuan; Zhang, Huiwen; Zhang, Chenggang (eLife, 2021)
Keywords: Amino acids; Animals; Antibodies; Antigens; B-Lymphocytes - immunology; Bone marrow; CD4 antigen; CD8 antigen; Cell differentiation; cell-mediated immunity; Cross Protection; Cytokines; Cytotoxicity; Dendritic cells; Epidemiology and Global Health; Epitopes; Epitopes - immunology; Female; Genomes; Helper cells; Hemagglutinin Glycoproteins, Influenza Virus - immunology; hemagglutinin stalk; Hemagglutinins; Immune response (cell-mediated); Immunity, Cellular; Immunoglobulins; Immunology and Inflammation; Infections; Influenza; Influenza A virus - genetics; Influenza A virus - immunology; Influenza A Virus, H1N1 Subtype - immunology; Influenza Vaccines - immunology; Lymphocytes; Lymphocytes T; Mice; Mice, Inbred BALB C; Orthomyxoviridae; Orthomyxoviridae Infections - prevention & control; Pandemics; Phylogenetics; Proteins; Public health; Rabies; Recombinant Proteins - immunology; RNA polymerase; superantigen; Superantigens - immunology; T-Lymphocytes - immunology; Vaccination; Vaccines; Viruses; global health; epidemiology; mouse; hemagglutinin stalk; inflammation; superantigen; immunology; cross-protection; cell-mediated immunity