The broad effects of the functional IL-10 promoter-592 polymorphism: modulation of IL-10, TIMP-3, and OPG expression and their association with periodontal disease outcome - Marcela Claudino; Ana Paula F. Trombone; Cristina R. Cardoso; Samuel B. Ferreira, Jr; Walter Martins, Jr; Gerson F. Assis; Carlos F. Santos; Paula C. Trevilatto; Ana Paula Campanelli; João S. Silva; Gustavo P. Garlet (Journal of leukocyte biology, 2008)
Keywords: Adult; Case-Control Studies; Chronic Periodontitis - genetics; cytokine; Female; genetic polymorphism; Genotype; Gingiva - metabolism; Gingiva - pathology; Humans; immunoregulation; Interleukin-10 - genetics; interleukin‐10; Male; Middle Aged; osteoprotegerin; Osteoprotegerin - genetics; periodontal disease; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide - genetics; Promoter Regions, Genetic - genetics; Regulatory Sequences, Nucleic Acid; RNA, Messenger - genetics; RNA, Messenger - metabolism; single nucleotide polymorphism; Tissue Inhibitor of Metalloproteinase-3 - genetics