Carrier-bound platinum and iron compounds with carcinostatic properties

• Published in: Polymers for advanced technologies Vol. 9; no. 10-11; pp. 786 - 793
• Main Author: Neuse, Eberhard W.
• Format: Journal Article
• Language: English
• Published: Chichester, UK John Wiley & Sons, Ltd 01.10.1998
• Subjects: Agents; Amines; Cell culture; Chelation; Controlled drug delivery; Derivatives; ferrocene; HeLa cell line; Iron compounds; Metallorganic polymers; Platinum compounds; platinum(II) complexes; Solubility; water-soluble polymeric carriers

The treatment of malignancies with carcinostatic drugs, per se or in combination with other modalities, has proved its value over many decades of clinical administration. However, despite much progress in drug research in recent years, complete cures by chemotherapy are still restricted to a small s...