Pectinase responsive nanoplatform for oral targeted delivery 5-aminosalicylic acid and zinc coordination driven nanozyme in inflammatory bowel disease treatment

• Published in: International journal of pharmaceutics: X Vol. 10; p. 100362
• Main Authors: Lin, Yiting, Fang, Siqi, Chen, Xinyi, Li, Xiang, Zhao, Xinlin, Wang, Yanwen, Lu, Jing, Ji, Qingdong, Zheng, Shuhui, Zou, Jiafeng, Qi, Chendong, Gao, Feng
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.12.2025; Elsevier
• Subjects: 5-aminosalicylic acid; Chitosan; Hyaluronic acid; Inflammatory bowel disease; Pectin; Research Paper; Zinc coordination driven nanozyme; Inflammatory bowel disease; Pectin; Zinc coordination driven nanozyme; Chitosan; Hyaluronic acid; 5-aminosalicylic acid

Characterized by weight loss, intestinal ulcerations, and diarrhea with blood or mucus, inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, is a chronic gastrointestinal condition. The rising incidence of IBD is placing pressure on healthcare systems globall...