Safety and immunogenicity of a 13-valent pneumococcal conjugate vaccine

• Published in: Pediatrics (Evanston) Vol. 125; no. 5; p. 866
• Main Authors: Bryant, Kristina A, Block, Stan L, Baker, Sherryl A, Gruber, William C, Scott, Daniel A
• Format: Journal Article
• Language: English
• Published: United States 01.05.2010
• Subjects: Antibodies, Bacterial - blood; Drug-Related Side Effects and Adverse Reactions; Female; Heptavalent Pneumococcal Conjugate Vaccine; Humans; Immunization Schedule; Infant; Male; Pneumococcal Infections - immunology; Pneumococcal Infections - prevention & control; Pneumococcal Vaccines - administration & dosage; Pneumococcal Vaccines - immunology; Serotyping; Streptococcus pneumoniae - immunology

Invasive pneumococcal disease rates have declined since immunization with 7-valent pneumococcal conjugate vaccine (PCV7) (Prevenar/Prevnar [Wyeth Pharmaceuticals, Philadelphia, PA]) became routine. Certain nonvaccine Streptococcus pneumoniae serotypes (1, 3, 5, 6A, 7F, and 19A) still cause significa...