Effect of Plasma from Patients with Idiopathic Nephrotic Syndrome on Proteoglycan Synthesis by Human and Rat Glomerular Cells

• Published in: Pediatric research Vol. 43; no. 4; pp. 489 - 495
• Main Authors: Girardin, Eric P, Birmele, Beatrice, Benador, Nadine, Neuhaus, Thomas, Hosseini, Ghamartaj, van den Heuvel, Lambertus P W J, de Agostini, Ariane
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.04.1998
• Subjects: Animals; Biological and medical sciences; Blood - metabolism; Cell Division; Cell Survival; Cells, Cultured; Culture Media; Enzyme-Linked Immunosorbent Assay; Glomerulonephritis; Glomerulonephritis, Membranous - blood; Humans; Kidney Glomerulus - cytology; Kidney Glomerulus - metabolism; Medical sciences; Nephrology. Urinary tract diseases; Nephropathies. Renovascular diseases. Renal failure; Nephrotic Syndrome - blood; Proteoglycans - biosynthesis; Rats; Serum Albumin - metabolism; Human; Glomerulonephritis; Kidney disease; Human origin; Proteoglycan; Cell culture; Urinary system disease; Rat; Pathogenesis; Rodentia; Idiopathic; Biosynthesis; Nephrotic syndrome; In vitro; Blood plasma; Renal glomerulus; Vertebrata; Mammalia; Animal; Biological effect; Child

In vivo and in vitro findings have shown that plasma of patients with idiopathic nephrotic syndrome (INS) contain factors that increase glomerular permeability to proteins. The effects of these factors on proteoglycan synthesis by glomerular cells are unknown. To investigate the effect of plasma fro...