Pain scores and ventilatory and circulatory sequelae of epidural morphine in cancer patients with and without prior narcotic therapy

• Published in: Anesthesia and analgesia Vol. 67; no. 9; pp. 838 - 842
• Main Authors: PFEIFER, B. L, SERNAKER, H. L, TER HORST, U. M
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott 01.09.1988
• Subjects: Adult; Aged; Anesthesia; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Blood Pressure - drug effects; Epidural Space; Female; Heart Rate - drug effects; Hemodynamics - drug effects; Humans; Injections, Epidural; Local anesthesia. Pain (treatment); Male; Medical sciences; Middle Aged; Morphine - administration & dosage; Morphine - pharmacology; Morphine - therapeutic use; Neoplasms - drug therapy; Respiration - drug effects; Human; Regional anesthesia; Pain; Extradural administration; Local anesthesia; Tumor; Hemodynamics; Narcotic analgesic

Pain scores and respiratory and circulatory sequelae of epidural morphine were studied in 25 patients with cancer, classified into two groups: 15 with and 10 without a history of previous narcotic analgesic therapy. Morphine, 2.5 mg initially and 5.0 mg 12 hours later, was given through an indwellin...