Changes in plasma and amniotic fluid endothelin levels during pregnancy: Facts or artefacts?

• Published in: European journal of obstetrics & gynecology and reproductive biology Vol. 76; no. 1; pp. 15 - 19
• Main Authors: Carbonne, B, Mignot, T.M, Tsatsaris, V, Ferré, F
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 1998; Elsevier
• Subjects: Amniotic fluid; Amniotic Fluid - metabolism; Biological and medical sciences; Endothelin-1 - blood; Endothelin-1 - metabolism; Endothelin-2 - blood; Endothelin-2 - metabolism; Endothelin-3 - blood; Endothelin-3 - metabolism; Endothelins; Endothelins - blood; Endothelins - metabolism; Female; Fundamental and applied biological sciences. Psychology; Gestational Age; Hormone metabolism and regulation; Humans; Labor, Obstetric - blood; Labor, Obstetric - metabolism; Parturition; Pregnancy; Pregnancy - blood; Pregnancy - metabolism; Pregnancy. Parturition. Lactation; Radioimmunoassay; Reagent Kits, Diagnostic; Vertebrates: reproduction; Pregnancy; Parturition; Endothelins; Amniotic fluid; Human; Endothelin; Radioimmunoassay; Peptide hormone; Vasoconstrictor agent; Evolution; Female; Gestational age; Blood plasma

Objective: To describe the evolution of immunoreactive endothelins (irETs) in maternal peripheral plasma and in amniotic fluid at different stages of pregnancy using two different radioimmunoassays. Study design: Peripheral blood samples were obtained from ten non-pregnant and eighty-four pregnant p...