Oral delivery of alloantigen combined with non-depleting anti-CD4 monoclonal antibody induces indefinite survival of cardiac allografts and generates CD4 + regulatory T cells

• Published in: Transplantation proceedings Vol. 32; no. 7; p. 2035
• Main Authors: Niimi, M, Ikeda, Y, Shirasugi, N, Shatari, T, Takami, H, Kodaira, S, Matsumoto, K, Hamano, K, Esato, K, Hara, M, Wood, K.J
• Format: Journal Article Conference Proceeding
• Language: English
• Published: New York, NY Elsevier Inc 01.11.2000; Elsevier Science
• Subjects: Administration, Oral; Adoptive Transfer; Animals; Antibodies, Monoclonal - pharmacology; Biological and medical sciences; CD4 Antigens - immunology; CD4-Positive T-Lymphocytes - immunology; CD8-Positive T-Lymphocytes - immunology; Graft Survival - immunology; Heart Transplantation - immunology; Heart Transplantation - physiology; Immunosuppression - methods; Isoantigens - administration & dosage; Isoantigens - immunology; Lymphocyte Transfusion; Medical sciences; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the heart; Transplantation, Homologous; Heart; Prognosis; Thymus gland; Rodentia; Oral administration; Helper cell; Monoclonal antibody; Homotransplantation; Cell subpopulation; Survival; Vertebrata; Mammalia; Alloantigen; Treatment; Mouse; Animal; T-Lymphocyte