Oral delivery of alloantigen combined with non-depleting anti-CD4 monoclonal antibody induces indefinite survival of cardiac allografts and generates CD4 + regulatory T cells
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| Published in | Transplantation proceedings Vol. 32; no. 7; p. 2035 |
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| Main Authors | , , , , , , , , , , |
| Format | Journal Article Conference Proceeding |
| Language | English |
| Published |
New York, NY
Elsevier Inc
01.11.2000
Elsevier Science |
| Subjects | |
| Online Access | Get full text |
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| Author | Esato, K Ikeda, Y Takami, H Matsumoto, K Hamano, K Niimi, M Shirasugi, N Hara, M Kodaira, S Shatari, T Wood, K.J |
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| Keywords | Heart Prognosis Thymus gland Rodentia Oral administration Helper cell Monoclonal antibody Homotransplantation Cell subpopulation Survival Vertebrata Mammalia Alloantigen Treatment Mouse Animal T-Lymphocyte |
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| References | Niimi (BIB4) 1998; 6 Weiner (BIB1) 1997; 18 Niimi (BIB2) 1999; 31 Qin (BIB3) 1990; 20 Niimi (10.1016/S0041-1345(00)01546-3_BIB4) 1998; 6 Weiner (10.1016/S0041-1345(00)01546-3_BIB1) 1997; 18 Qin (10.1016/S0041-1345(00)01546-3_BIB3) 1990; 20 Niimi (10.1016/S0041-1345(00)01546-3_BIB2) 1999; 31 |
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| SubjectTerms | Administration, Oral Adoptive Transfer Animals Antibodies, Monoclonal - pharmacology Biological and medical sciences CD4 Antigens - immunology CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - immunology Graft Survival - immunology Heart Transplantation - immunology Heart Transplantation - physiology Immunosuppression - methods Isoantigens - administration & dosage Isoantigens - immunology Lymphocyte Transfusion Medical sciences Mice Mice, Inbred C57BL Mice, Inbred CBA Mice, Transgenic Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the heart Transplantation, Homologous |
| Title | Oral delivery of alloantigen combined with non-depleting anti-CD4 monoclonal antibody induces indefinite survival of cardiac allografts and generates CD4 + regulatory T cells |
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