New and revised gene ontology biological process terms describe multiorganism interactions critical for understanding microbial pathogenesis and sequences of concern

• Published in: Journal of biomedical semantics Vol. 16; no. 1; pp. 4 - 9
• Main Authors: Godbold, Gene, Proescher, Jody, Gaudet, Pascale
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 21.03.2025; BioMed Central; BMC
• Subjects: Animals; Biological activity; Cell cycle; Controlled vocabularies; Dual use research of concern; Exploitation; Gene Ontology; Genetic research; Host-Pathogen Interactions - genetics; Humans; Infectious diseases; Life sciences; Methods; Microbial genetics; Microbial pathogenesis; Microorganisms; Nucleic acids; Nucleotides; Ontologies; Ontology; Pathogenesis; Pathogenicity; Pathogens; Physiological aspects; Screening; Sequences; Synthetic nucleotide screening; Terminology as Topic; Toxicity; Toxins; Virulence; Web Ontology Language-OWL; United States; United States > US; Synthetic nucleotide screening; Ontologies; Dual use research of concern; Infectious diseases; Controlled vocabularies; Microbial pathogenesis

There is a new framework from the United States government for screening synthetic nucleic acids. Beginning in October of 2026, it calls for the screening of sequences 50 nucleotides or greater in length that are known to contribute to pathogenicity or toxicity for humans, regardless of the taxa fro...