A specific haplotype in potential miRNAs binding sites of secreted frizzled-related protein 1 (SFRP1) is associated with BMD variation in osteoporosis - Amjadi-Moheb, Fatemeh; Hosseini, Seyed Reza; Kosari-Monfared, Mohadeseh; Ghadami, Elham; Nooreddini, Hajighorban; Akhavan-Niaki, Haleh (Gene, 2018)
Keywords: 3' untranslated regions; 3' Untranslated Regions - genetics; Aged; algorithms; Alleles; binding sites; Binding Sites - genetics; bioinformatics; bone density; Bone Density - genetics; elderly; Female; femur; Femur Neck - metabolism; Genotype; genotyping; Haplotype; haplotypes; Haplotypes - genetics; Humans; Intercellular Signaling Peptides and Proteins - genetics; introns; lumbar spine; Lumbar Vertebrae - metabolism; Male; males; Membrane Proteins - genetics; microRNA; MicroRNAs - genetics; Middle Aged; mineral content; Osteoporosis; Osteoporosis - genetics; patients; people; polymerase chain reaction; Polymorphism, Restriction Fragment Length - genetics; Polymorphism, Single Nucleotide - genetics; regression analysis; restriction fragment length polymorphism; SFRP1; signal transduction; Single nucleotide polymorphism; Wnt Proteins - genetics; Wnt signaling pathway; WNT5b; Wnt signaling pathway; WNT5b; MFE; Osteoporosis; SFRP1; SNP; BMD; BMC; Single nucleotide polymorphism; Haplotype; PCR; RFLP; BMI