A multicentre study of antifungal susceptibility patterns among 350 Candida auris isolates (2009–17) in India: role of the ERG11 and FKS1 genes in azole and echinocandin resistance

• Published in: Journal of antimicrobial chemotherapy Vol. 73; no. 4; pp. 891 - 899
• Main Authors: Chowdhary, Anuradha, Prakash, Anupam, Sharma, Cheshta, Kordalewska, Milena, Kumar, Anil, Sarma, Smita, Tarai, Bansidhar, Singh, Ashutosh, Upadhyaya, Gargi, Upadhyay, Shalini, Yadav, Priyanka, Singh, Pradeep K, Khillan, Vikas, Sachdeva, Neelam, Perlin, David S, Meis, Jacques F
• Format: Journal Article
• Language: English
• Published: England 01.04.2018

Candida auris has emerged globally as an MDR nosocomial pathogen in ICU patients. We studied the antifungal susceptibility of C. auris isolates (n = 350) from 10 hospitals in India collected over a period of 8 years. To investigate azole resistance, ERG11 gene sequencing and expression profiling was...