Surface plasmon-enhanced fluorescence and surface-enhanced Raman scattering dual-readout chip constructed with silver nanowires: Label-free clinical detection of direct-bilirubin

• Published in: Biosensors & bioelectronics Vol. 213; p. 114440
• Main Authors: Sahoo, Smruti R., Huey-Jen Hsu, Sandy, Chou, Dev-Aur, Wang, Gou-Jen, Chang, Cheng-Chung
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 01.10.2022
• Subjects: bilirubin; biosensors; blood serum; Clinical detection; COVID-19 infection; death; detection limit; Direct bilirubin; Fluorescence; Hot spot; humans; liver; nanowires; Plasmon; pneumonia; Raman; silver; spectrometers; survival rate; Fluorescence; Raman; Direct bilirubin; Plasmon; Hot spot; Clinical detection

It has been found that the direct/total bilirubin ratio (D/T-BIL) is related to the survival rate of COVID-19 pneumonia. The presence of an excessive amount of bilirubin in human blood also causes liver and neurological damage, leading to death. Therefore, upon considering the adverse impact of the...