Photoredox ketone catalysis for the direct C-H imidation and acyloxylation of arenes

• Published in: Chemical science (Cambridge) Vol. 8; no. 8; pp. 5622 - 5627
• Main Authors: Tripathi, Chandra Bhushan, Ohtani, Tsuyoshi, Corbett, Michael T., Ooi, Takashi
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 01.08.2017
• Subjects: Chemistry; Chemistry, Multidisciplinary; Physical Sciences; Science & Technology; AMINATION; HETEROARENES; ENERGY; ELECTRON-TRANSFER; THIOXANTHONE; QUANTUM YIELDS; TERTIARY-AMINES; LIGHT; EFFICIENT; 2+2 PHOTOCYCLOADDITION REACTIONS

The photoexcited aryl ketone-catalyzed C-H imidation of arenes and heteroarenes is reported. Using 3,6-dimethoxy-9H-thioxanthen-9-one as a catalyst in combination with a bench-stable imidating reagent, C-N bond formation proceeds with high efficiency and a broad substrate scope. A key part of this m...