CMOS microcavity arrays for single-cell electroporation and lysis

• Published in: Biosensors & bioelectronics Vol. 150; p. 111931
• Main Authors: Punjiya, Meera, Mocker, André, Napier, Bradley, Zeeshan, Arif, Gutsche, Martin, Sonkusale, Sameer
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 15.02.2020
• Subjects: biosensors; cell viability; CMOS microelectrode array; electric field; electrodes; Electroporation; humans; kidney cells; Lab on a chip; Lab on CMOS; leaching; mathematical models; semiconductors; single cell analysis; Transfection; Lab on CMOS; Electroporation; CMOS microelectrode array; Transfection; single cell analysis; Lab on a chip

Transfection is a key function for many single-cell analyses. Reversible electroporation (EP) using high intensity electric fields is a simple means of transfection applicable to most cell types. For reversible EP, precise control over the electric field is critical to regulate the induced pore dens...