Induction of metachromasia in experimentally induced hyperplastic/hypertrophic changes in the prostate of the cynomolgus monkey (Macaca fascicularis)

• Published in: The Journal of urology Vol. 142; no. 6; p. 1624
• Main Authors: Habenicht, U F, el Etreby, M F, Lewis, R, Ghoniem, G, Roberts, J
• Format: Journal Article
• Language: English
• Published: United States 01.12.1989
• Subjects: Androstenedione - analogs & derivatives; Androstenedione - pharmacology; Animals; Aromatase Inhibitors; Macaca fascicularis; Male; Prostate - drug effects; Prostate - pathology; Prostatic Hyperplasia - chemically induced; Prostatic Hyperplasia - pathology; Staining and Labeling - methods

Metachromasia has been shown to be a stromal marker for human benign prostatic hyperplasia (BPH). So far, it is not known whether comparable changes can be demonstrated in experimentally induced BPH in the dog or in a subhuman primate species. In the present study, the phenomenon of metachromasia co...