Tunable external cavity quantum cascade laser for the simultaneous determination of glucose and lactate in aqueous phase

• Published in: Analyst (London) Vol. 135; no. 12; pp. 3260 - 3265
• Main Authors: BRANDSTETTER, Markus, GENNER, Andreas, ANIC, Kresimir, LENDL, Bernhard
• Format: Conference Proceeding Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 01.12.2010
• Subjects: Analytical chemistry; Aqueous solutions; Calibration; Chemistry; Density; Exact sciences and technology; Glucose; Glucose - analysis; Humans; Lactates; Lactic Acid - analysis; Lasers, Semiconductor; Maltose; Maltose - analysis; Mathematical models; Multivariate Analysis; Point-of-Care Systems; Quantum cascade lasers; Reproducibility of Results; Spectrophotometry, Infrared - instrumentation; Spectrophotometry, Infrared - methods; Spectroscopy, Fourier Transform Infrared - instrumentation; Spectroscopy, Fourier Transform Infrared - methods; Tuning; Water - analysis; Xylose - analysis; High density; Size; Glucose; Multivariate analysis; Mean square error; Improvement; Robustness; Root; Use; Interference; Prediction; Concentration; Calibration; Maltose; Monitoring system; Lactates; Optical measurement; PLS regression; Multicomponent analysis; Sample cell; Sodium; Laser; Simultaneous measurement; Reagents; Aqueous solution; Room temperature

A room temperature operated pulsed external-cavity (EC) quantum cascade laser (QCL) was used for mid-infrared (mid-IR) transmission measurements of glucose and lactate in aqueous solution. The high spectral power density of the EC-QCL (ranging from 1-350 mW) over a wide tuning range (1030-1230 cm(-1...