Detection of Serum-Specific IgE by Fluoro-Enzyme Immunoassay for Diagnosing Type I Hypersensitivity Reactions to Penicillins

• Published in: International journal of molecular sciences Vol. 23; no. 13; p. 6992
• Main Authors: Ariza, Adriana, Mayorga, Cristobalina, Bogas, Gádor, Gaeta, Francesco, Salas, María, Valluzzi, Rocco L., Labella, Marina, Pérez-Sánchez, Natalia, Caruso, Cristiano, Molina, Ana, Fernández, Tahia D., Torres, María José, Romano, Antonino
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 01.07.2022; MDPI
• Subjects: Allergies; Enzymes; Immunoassay; Patients; Penicillin; Italy; Spain

Diagnosis of type I hypersensitivity reactions (IgE-mediated reactions) to penicillins is based on clinical history, skin tests (STs), and drug provocation tests (DPTs). Among in vitro complementary tests, the fluoro-enzyme immunoassay (FEIA) ImmunoCAP® (Thermo-Fisher, Waltham, MA, USA) is the most...