A comparative study between the Chrono-log 700 and the Sysmex CS-2100i analyzers for assessing ristocetin cofactor activity in patients with von Willebrand disease

• Published in: Journal of laboratory medicine Vol. 49; no. 4; pp. 149 - 154
• Main Authors: Boulassel, Mohamed-Rachid, Abdellatif, Hussein, Al-Falahi, Karima, Al-Hashmi, Fatma, Bouchareb, Yassine, Al-Abri, Buthaina, Al-Jahdhami, Habib
• Format: Journal Article
• Language: English
• Published: De Gruyter 26.08.2025
• Subjects: automation; ristocetin co-factor activity; von Willebrand disease

A variety of methods are currently used to measure von Willebrand factor (VWF) activity, but still the VWF ristocetin cofactor (VWF:RCo) assay using the manual aggregometry technique is the reference method, even having high inter-laboratory variability. The automated coagulation analyzers offer sev...