An efficient ratiometric fluorescence sensor based on metal-organic frameworks and quantum dots for highly selective detection of 6-mercaptopurine

• Published in: Biosensors & bioelectronics Vol. 91; pp. 162 - 168
• Main Authors: Jin, Meng, Mou, Zhao-Li, Zhang, Rui-Ling, Liang, Si-Si, Zhang, Zhi-Qi
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 15.05.2017
• Subjects: 3-Mercaptopropionic Acid - chemistry; 6-Mercaptopurine; adverse effects; Biosensing Techniques - methods; biosensors; Cadmium Compounds - chemistry; CdTe quantum dots; coordination polymers; detection limit; environmental factors; fluorescence; Fluorescent Dyes - chemistry; Humans; Inner filter effect; Limit of Detection; Mercaptopurine - urine; Metal-organic frameworks; Organometallic Compounds - chemistry; quantitative analysis; quantum dots; Quantum Dots - chemistry; Quantum Dots - ultrastructure; Ratiometric fluorescence sensor; Spectrometry, Fluorescence - methods; Tellurium - chemistry; urine; wavelengths; 6-Mercaptopurine; Inner filter effect; CdTe quantum dots; Ratiometric fluorescence sensor; Metal-organic frameworks

The development of a simple and accurate quantitative method for the determination of 6-mercaptopurine (6-MP) is of great importance because of its serious side effects. Ratiometric fluorescence (RF) sensors are not subject to interference from environmental factors, and exhibit enhanced precision a...