Pathophysiology of Diverticular Disease: From Diverticula Formation to Symptom Generation

• Published in: International journal of molecular sciences Vol. 23; no. 12; p. 6698
• Main Authors: Barbaro, Maria Raffaella, Cremon, Cesare, Fuschi, Daniele, Marasco, Giovanni, Palombo, Marta, Stanghellini, Vincenzo, Barbara, Giovanni
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 15.06.2022; MDPI
• Subjects: Asymptomatic; Cell cycle; Collagen; Colon; Colorectal cancer; Diet; Diverticulitis; Extracellular matrix; Genes; Inflammation; Irritable bowel syndrome; Mutation; Nervous system; Pathogenesis; Pathophysiology; Population; Proteins; Review; Vegetarianism; United Kingdom > UK

Diverticular disease is a common clinical problem, particularly in industrialized countries. In most cases, colonic diverticula remain asymptomatic throughout life and sometimes are found incidentally during colonic imaging in colorectal cancer screening programs in otherwise healthy subjects. Nonet...