Evaluation of 24-hour growth hormone spontaneous secretion: comparison with a nocturnal and diurnal 12-hour study

• Published in: Hormone research Vol. 35; no. 1; p. 25
• Main Authors: Saggese, G, Cesaretti, G, Cinquanta, L, Giannessi, N, Bracaloni, C, Di Spigno, G, Cioni, C
• Format: Journal Article
• Language: English
• Published: Switzerland 1991
• Subjects: Child; Child, Preschool; Circadian Rhythm; Female; Growth Disorders - physiopathology; Growth Hormone - deficiency; Growth Hormone - secretion; Humans; Hypoglycemia - chemically induced; Hypoglycemia - physiopathology; Insulin; Levodopa; Male; Puberty

Spontaneous growth hormone (GH) secretion in 116 short children was studied by sampling blood for GH measurement every 20 min over 24 h. We calculated 24-h mean GH concentration (MGHC), diurnal 12-h MGHC (dMGHC) and nocturnal 12-h MGHC (nMGHC). The children were subdivided into four groups: prepuber...