Origin and pathogenesis of pelvic (ovarian, tubal, and primary peritoneal) serous carcinoma

• Published in: Annual review of pathology Vol. 9; p. 27
• Main Authors: Nik, Niloofar N, Vang, Russell, Shih, Ie-Ming, Kurman, Robert J
• Format: Journal Article
• Language: English
• Published: United States 01.01.2014
• Subjects: Animals; Carcinoma in Situ - genetics; Carcinoma in Situ - pathology; Carcinoma, Ovarian Epithelial; Cystadenocarcinoma, Serous - genetics; Cystadenocarcinoma, Serous - pathology; Fallopian Tube Neoplasms - genetics; Fallopian Tube Neoplasms - pathology; Female; Humans; Neoplasms, Glandular and Epithelial - genetics; Neoplasms, Glandular and Epithelial - pathology; Ovarian Neoplasms - genetics; Ovarian Neoplasms - pathology

A new paradigm for the pathogenesis of female pelvic cancer helps explain persistent problems in describing the development and diverse morphology of these neoplasms. This paradigm incorporates recent advances in the molecular pathogenesis of epithelial ovarian cancer (EOC) with new insights into th...