Bromadiolone may cause severe acute kidney injury through severe disorder of coagulation: a case report

• Published in: BMC nephrology Vol. 25; no. 1; pp. 303 - 6
• Main Authors: Wang, Han, Deng, Lingling, Sun, Bin, Xing, Changying, Mao, Huijuan, Wu, Buyun
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 12.09.2024; BioMed Central; BMC
• Subjects: 4-Hydroxycoumarins - poisoning; Abdomen; Acute kidney injury; Acute Kidney Injury - chemically induced; Acute renal failure; Adult; Anticoagulant rodenticide; Anticoagulants; Anticoagulants (Medicine); Anticoagulants - adverse effects; Biopsy; Blood; Blood clotting disorders; Blood Coagulation Disorders - chemically induced; Bromadiolone; Case studies; Coagulopathy; Complications and side effects; Creatinine; Dosage and administration; Female; Gas chromatography; Health aspects; Hematuria; Hemoglobin; Hemorrhage; Hospitals; Humans; Kidneys; Mass spectroscopy; Patients; Pharmacology, Experimental; Physiological aspects; Poisoned; Poisoning; Poisons; Prothrombin; Renal function; Risk factors; Rodenticides; Rodenticides - poisoning; Ultrasonic imaging; Urine; Vitamin deficiency; Vitamin K; Vitamin K - therapeutic use; Vitamin K antagonists; China; Poisoned; Anticoagulant rodenticide; Bromadiolone; Acute kidney injury; Vitamin K antagonists; Coagulopathy

Bromadiolone is a wide-use long-acting anticoagulant rodenticide known to cause severe coagulation dysfunction. At present, there have been no detailed reports of acute kidney injury (AKI) resulting from bromadiolone poisoning. A 27-year-old woman was admitted to the hospital due to severe coagulopa...