Oscillatory shear stress promotes endothelial senescence and atherosclerosis via STING activation - Dong, Mengdie; Chen, Minghong; Zhang, Yunjia; He, Xian; Min, Jiao; Tan, Yongkang; Wei, Huiyuan; Li, Xinyu; Chen, Xiang; Zheng, Longbin; Yin, Quanwen; Li, Xuesong; et al. (Biochemical and biophysical research communications, 2024)
Keywords: Animals; atherogenesis; Atherosclerosis; Atherosclerosis - genetics; Atherosclerosis - metabolism; Atherosclerosis - pathology; blood flow; Cells, Cultured; Cellular Senescence - genetics; Diet, High-Fat; DNA, Mitochondrial - genetics; DNA, Mitochondrial - metabolism; Endothelial Cells - metabolism; Endothelial Cells - pathology; Endothelial senescence; Endothelium, Vascular - metabolism; Endothelium, Vascular - pathology; high fat diet; Humans; Membrane Proteins - genetics; Membrane Proteins - metabolism; Mice; Mice, Inbred C57BL; mitochondria; Mitochondria - metabolism; Mitochondria - pathology; mitochondrial DNA; Oscillatory shear stress; shear stress; STING; Stress, Mechanical; therapeutics; STING; Oscillatory shear stress; Atherosclerosis; Endothelial senescence