In situ synthesis of magnetic CaraPVA IPN nanocomposite hydrogels and controlled drug release

• Published in: Materials Science & Engineering C Vol. 45; pp. 250 - 260
• Main Authors: Mahdavinia, Gholam Reza, Etemadi, Hossein
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.12.2014
• Subjects: Adsorption; Anti-Bacterial Agents - chemistry; Anti-Bacterial Agents - pharmacology; Bacteria; Carrageenan - chemistry; Diclofenac - chemistry; Diclofenac - pharmacology; Drug Carriers - chemical synthesis; Drug Carriers - chemistry; Drug delivery systems; Drug Liberation; Drug release; Drugs; Ferrosoferric Oxide - chemistry; Hydrogel; Hydrogels; Hydrogels - chemical synthesis; Hydrogels - chemistry; Hydrogen-Ion Concentration; kappa-Carrageenan; Magnetic; Magnetic Fields; Magnetite Nanoparticles - chemistry; Microscopy, Electron, Scanning; Mucins - chemistry; Nanoparticles; Nanostructure; Polyvinyl alcohol; Polyvinyl Alcohol - chemistry; Polyvinyl alcohols; Scanning electron microscopy; Spectroscopy, Fourier Transform Infrared; Staphylococcus aureus - drug effects; Thermogravimetry; X-Ray Diffraction; Drug release; kappa-Carrageenan; Polyvinyl alcohol; Magnetic; Hydrogel

In this work, the magnetic nanocomposite hydrogels that focused on targeted drug delivery were synthesized by incorporation of polyvinyl alcohol (PVA), kappa-carrageenan (Cara), and magnetite Fe3O4 nanoparticles. The magnetic nanoparticles were obtained in situ in the presence of a mixture of polyvi...