The social shape of sperm: using an integrative machine-learning approach to examine sperm ultrastructure and collective motility

• Published in: Proceedings of the Royal Society. B, Biological sciences Vol. 288; no. 1959; p. 20211553
• Main Authors: Hook, Kristin A, Yang, Qixin, Campanello, Leonard, Losert, Wolfgang, Fisher, Heidi S
• Format: Journal Article
• Language: English
• Published: England The Royal Society 29.09.2021
• Subjects: Animals; Evolution; Female; Machine Learning; Male; Mice; Sperm Head; Sperm Motility; Sperm-Ovum Interactions; Spermatozoa; automated morphometrics; collective motion; cell morphology; peromyscus; sperm aggregation; sperm conjugation

Sperm is one of the most morphologically diverse cell types in nature, yet they also exhibit remarkable behavioural variation, including the formation of collective groups of cells that swim together for motility or transport through the female reproductive tract. Here, we take advantage of natural...