Role of tyrosine kinase-independent phosphorylation of EGFR with activating mutation in cisplatin-treated lung cancer cells

Epidermal growth factor receptor (EGFR) mutation is one of the hallmarks of cancer progression and resistance to anticancer therapies, particularly non-small cell lung carcinomas (NSCLCs). In contrast to the canonical EGFR activation in which tyrosine residues are engaged, we have demonstrated that...

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Bibliographic Details
Published inBiochemical and biophysical research communications Vol. 458; no. 4; pp. 856 - 861
Main Authors Refaat, Alaa, Aminullah, Zhou, Yue, Kawanishi, Miho, Tomaru, Rika, Abdelhamed, Sherif, Shin, Myoung-Sook, Koizumi, Keiichi, Yokoyama, Satoru, Saiki, Ikuo, Sakurai, Hiroaki
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 20.03.2015
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