Injectable nanomaterials for drug delivery: Carriers, targeting moieties, and therapeutics

• Published in: European journal of pharmaceutics and biopharmaceutics Vol. 84; no. 1; pp. 1 - 20
• Main Authors: Webster, David M., Sundaram, Padma, Byrne, Mark E.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.05.2013
• Subjects: Animals; Clinical Trials as Topic - methods; Drug Carriers - administration & dosage; Drug delivery carriers; Drug Delivery Systems - methods; Humans; Injectable nanoparticles; Injections; Liposomes; Nanocarriers; Nanostructures - administration & dosage; Neoplasms - diagnosis; Neoplasms - drug therapy; Targeting moieties; Therapeutics; Targeting moieties; Injectable nanoparticles; Nanocarriers; Drug delivery carriers; Therapeutics

Generalized nanomedicine carrier. Structure composed of a core material containing both a hydrophobic and hydrophilic region, surface modifiers, and therapeutic payload. Therapeutics such as nucleic acids, proteins/peptides, vaccines, anti-cancer, and other drugs have disadvantages of low bio-availa...