Ultrasound-and MR-guided focused ultrasound surgery for prostate cancer

Prostate cancer(PC) is one of the most frequently diagnosed cancers in men.There are a number of treatment options for PC with a different therapeutic approach between USA and Europe.Radical prostatectomy is one of the most used therapies but focal gland therapy is an emerging approach,especially fo...

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Bibliographic Details
Published inWorld journal of radiology Vol. 4; no. 6; pp. 247 - 252
Main Authors Zini, Chiara, Hipp, Elisabeth, Thomas, Stephen, Napoli, Alessandro, Catalano, Carlo, Oto, Aytekin
Format Journal Article
LanguageEnglish
Published United States Baishideng Publishing Group Co., Limited 28.06.2012
Subjects
cancer
focused
guided
High
intensity
Magnetic
Prostate
resonance
Review
surgery
ultrasound
Prostate cancer
Magnetic resonance guided focused ultrasound surgery
High intensity focused ultrasound
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Summary:Prostate cancer(PC) is one of the most frequently diagnosed cancers in men.There are a number of treatment options for PC with a different therapeutic approach between USA and Europe.Radical prostatectomy is one of the most used therapies but focal gland therapy is an emerging approach,especially for localized tumors.In this scenario,high intensity focused ultrasound(HIFU) has been incorporated in certain medical association guidelines.HIFU has been employed for about 10 years especially for localized PC.Results are promising with a 5-year biochemical survival rate ranging from 45% to 84%.Collateral events are rare and HIFU retreatment is not common.Magnetic resonance guided focused ultrasound surgery(MRgFUS) was recently presented as a method for ablation with focused ultrasound under magnetic resonance imaging guidance.It has the advantage of improved targeting and real time temperature monitoring but only a few studies have been conducted with human patients.The aim of this review is to describe the current status of HIFU and MRgFUS in the therapy of PC.
Bibliography:Chiara Zini,Alessandro Napoli,Carlo Catalano,Department of Radiological,Oncological and Pathological Sciences,Sapienza University of Rome,00161 Rome,Italy Elisabeth Hipp,Stephen Thomas,Aytekin Oto,Department of Radiology,The University of Chicago,Chicago,IL 60637,United States
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Telephone: +1-773-7028553 Fax: + 1-773-7021161
Author contributions: Zini C and Oto A contributed to data collection, analysis, manuscript preparation, and the decision to submit for publication; Hipp E, Napoli A, Thomas S and Catalano C contributed to manuscript preparation, and the decision to submit for publication.
Correspondence to: Aytekin Oto, MD, Department of Radiology, The University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, United States. aoto@radiology.bsd.uchicago.edu
ISSN:1949-8470
1949-8470
DOI:10.4329/wjr.v4.i6.247