Molecular mechanisms of synergistic induction of apoptosis by the combination therapy with hyperthermia and cisplatin in prostate cancer cells - Zhang, Jian-fu; Yan, Xiang-ming; Lan, Bin; Lei, Yin-rui; Li, Xiao-hu; Gao, Shuai; Guo, Yi-feng; Guo, Fang (Biochemical and biophysical research communications, 2016)
Keywords: Animals; Antineoplastic Agents - pharmacology; Apoptosis; Apoptosis - drug effects; Apoptosis Regulatory Proteins - metabolism; Blotting, Western; Caspase 3 - metabolism; caspase-3; Cell Line, Tumor; Cell Proliferation - drug effects; Cell Survival - drug effects; cell viability; Cisplatin; Cisplatin - pharmacology; Combination therapy; disease course; dose response; Dose-Response Relationship, Drug; drug therapy; fever; Hot Temperature; Humans; Hyperthermia; Inhibitor of Apoptosis Proteins - metabolism; Male; males; mortality; neoplasm cells; Poly (ADP-Ribose) Polymerase-1 - metabolism; Prostate cancer; prostatic neoplasms; Prostatic Neoplasms - metabolism; Prostatic Neoplasms - pathology; proteins; Proto-Oncogene Proteins c-bcl-2 - metabolism; signal transduction; Signal Transduction - drug effects; synergism; Time Factors; United States; Western blotting; United States; Combination therapy; Hyperthermia; Prostate cancer; Cisplatin; Apoptosis