Revaccination of Children after Completion of Standard Chemotherapy for Acute Leukemia

• Published in: Clinical infectious diseases Vol. 44; no. 5; pp. 635 - 642
• Main Authors: Patel, Soonie R., Ortín, Miguel, Cohen, Bernard J., Borrow, Ray, Irving, Diane, Sheldon, Joanne, Heath, Paul T.
• Format: Journal Article
• Language: English
• Published: United States The University of Chicago Press 01.03.2007; University of Chicago Press; Oxford University Press
• Subjects: Acute Disease; Adolescent; Antibodies; Articles and Commentaries; Bacterial Capsules; Chemotherapy; Child; Child, Preschool; Children; Children & youth; Diphtheria Toxoid - administration & dosage; Diphtheria Toxoid - immunology; Haemophilus Vaccines - administration & dosage; Haemophilus Vaccines - immunology; Humans; Immunization; Immunization Schedule; Immunosuppressive Agents - therapeutic use; Infant; Leukemia; Leukemia, Myeloid - drug therapy; Leukemia, Myeloid - immunology; Lymphocytic leukemia; Measles; Measles Vaccine - administration & dosage; Measles Vaccine - immunology; Meningococcal Vaccines - administration & dosage; Meningococcal Vaccines - immunology; Monoclonal antibodies; Mumps Vaccine - administration & dosage; Mumps Vaccine - immunology; Myeloid leukemia; Neisseria meningitidis; Poliovirus Vaccines - administration & dosage; Poliovirus Vaccines - immunology; Polysaccharides, Bacterial - administration & dosage; Polysaccharides, Bacterial - immunology; Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy; Precursor Cell Lymphoblastic Leukemia-Lymphoma - immunology; Rubella Vaccine - administration & dosage; Rubella Vaccine - immunology; Tetanus; Tetanus Toxoid - administration & dosage; Tetanus Toxoid - immunology; Vaccination; Vaccines - immunology; Vaccines, Acellular - administration & dosage; Vaccines, Acellular - immunology

Background. After the treatment of patients with acute leukemia, there is a decrease in vaccine-specific antibody and an increased susceptibility to certain vaccine-preventable diseases. A simple revaccination schedule is warranted. Method. Fifty-nine children (age, 1–18 years) who had completed sta...