Risk stratification of heart failure from one drop of blood using hand-held biosensor for BNP detection

• Published in: Biosensors & bioelectronics Vol. 107; pp. 259 - 265
• Main Authors: Sarangadharan, Indu, Wang, Shin-Li, Tai, Tse-Yu, Pulikkathodi, Anil Kumar, Hsu, Chen-Pin, Chiang, Hui-Hua Kenny, Liu, Lawrence Yu-Min, Wang, Yu-Lin
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 01.06.2018
• Subjects: biomarkers; biosensors; blood cells; blood sampling; BNP; brain; cost effectiveness; detection limit; diagnostic techniques; Extended gate EDL FET biosensor; gravity; Hand-held device; Heart failure; industry; ionic strength; mortality; natriuretic peptides; proteins; risk assessment; screening; transistors; Whole blood diagnostics; Heart failure; Whole blood diagnostics; Hand-held device; Extended gate EDL FET biosensor; BNP

Continued risk assessment by evaluating cardiac biomarkers in healthy and unhealthy individuals can lower the mortality rate of cardiovascular diseases (CVDs). In this research, we have developed a hand-held biosensor system to rapidly screen for brain natriuretic peptide (BNP) from a single drop of...