Crucial players in glycolysis: Cancer progress

• Published in: Gene Vol. 726; p. 144158
• Main Authors: Abbaszadeh, Zaka, Çeşmeli, Selin, Biray Avcı, Çığır
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 05.02.2020
• Subjects: Adenosine Triphosphate - metabolism; Animals; apoptosis; Apoptosis - physiology; biochemical pathways; Cancer; death; Disease Progression; energy; enzymes; genes; Glcolysis; glucose; Glucose - metabolism; glycolysis; Glycolysis - physiology; Glycolytic enzymes; Humans; Lactic Acid - metabolism; lactic fermentation; methodology; Mitochondria - metabolism; Mitochondria - pathology; neoplasm cells; Neoplasms - metabolism; Neoplasms - pathology; Oxidative phosphorylation (OXPHOS); therapeutics; HK; PFKFBs; G3P; Oxidative phosphorylation (OXPHOS); LncRNA; Glcolysis; OXPHOS; HIF-1α; SLC; ADP; PI3K; SDH; mTOR; PFK2; H2B; Abhd5; G6PD; GLUTs; 3′UTR; TSC2; HGFR; TSC1; DHAP; EMT; F-1,6-P; PGI; TCA; CRC; PGK; PGM; ROS; AMPK; PIP3; GAPDH; mTORC1; FH; miRNAs; DERL3; CO2; ENO; RTK; TPI; EGFR; HSPs; LUAD; HIF-1; LDH; PPP; PTTG; NADH; PDH; PDK; c-Met; Glycolytic enzymes; G6P; GLUT1; TIGAR; GLUT3; HIF; NSCLC; SGLT2; CAV1; IDH1; SGLT1; VEGF; GRP78; HMGA1; TRAP-1; Acetyl-CoA; NAD; DNA; VDAC; HRE; PEP; SGLT; PK; GLUT4; ATP; GTPase; PFKM; PET; Cancer

•Since there is no exact cure discovered for cancer, studies have focused on different hallmarks of cancer.•Warburg’s hypothesis has been a step for the studies in this subject.•With the knowledge of crucial players in glycolysis takes place in cancer cells, therapies will be more accurate. Cancer i...