Effect of a gonadotropin-releasing hormone agonist on luteinizing hormone receptors and steroidogenesis in ovarian cells

• Published in: Fertility and sterility Vol. 59; no. 4; pp. 803 - 809
• Main Authors: Guerrero, Hernán E., Stein, Paula, Asch, Ricardo H., de Fried, Ester Polak, Tesone, Marta
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.04.1993; Elsevier Science
• Subjects: Animals; Biological and medical sciences; Birth control; Cells, Cultured; Estradiol - biosynthesis; Female; GnRH-a; granulosa cells; Granulosa Cells - drug effects; Granulosa Cells - metabolism; Gynecology. Andrology. Obstetrics; Humans; Leuprolide - pharmacology; LH receptors; luteal cells; Medical sciences; Progesterone - biosynthesis; Prospective Studies; Rats; Rats, Sprague-Dawley; Receptors, LH - analysis; Receptors, LH - drug effects; Sterility. Assisted procreation; steroidogenesis; steroidogenesis; luteal cells; LH receptors; granulosa cells; GnRH-a; Human; Agonist; Gonadotropin RH; Gonadotropin; Glycoprotein hormone; HCG; In vitro; Biological activity; Placental hormone; Hypothalamic hormone; Ovary; Adenohypophyseal hormone; Steroidogenesis; Granulosa; Hormone releasing factor; LH; Ovarian follicle; Hormonal receptor

To examine the effect of a gonadotropin-releasing hormone agonist (GnRH-a), leuprolide acetate (LA), on human chorionic gonadotropin/luteinizing hormone (LH) receptors content and progesterone (P) and estradiol (E2) production in cultured granulosa or luteal cells. Prospective. Private Fertility Cli...