Correlation of in vitro and in vivo acetaminophen availability from albumin microaggregates oral modified release formulations - Torrado, G.; Carrascosa, C.; Torrado-Santiago, S. (International journal of pharmaceutics, 2001)
Keywords: Acetaminophen; Acetaminophen - chemistry; Acetaminophen - pharmacokinetics; Acetaminophen - urine; Administration, Oral; Adult; Albumin microaggregates; Analgesics, Non-Narcotic - chemistry; Analgesics, Non-Narcotic - pharmacokinetics; Analgesics, Non-Narcotic - urine; Biological and medical sciences; Biological Availability; Chemistry, Pharmaceutical; Female; General pharmacology; Humans; Intestinal Absorption; Male; Medical sciences; Ovalbumin - chemistry; Ovalbumin - pharmacokinetics; Ovalbumin - urine; Pharmaceutical technology. Pharmaceutical industry; Pharmacology. Drug treatments; Saliva - metabolism; Site-specific drug delivery; Acetaminophen; Albumin microaggregates; Site-specific drug delivery; Human; Urine; Pharmaceutical technology; Healthy subject; Controlled release form; Oral administration; Albumin; Oral form; Drug carrier; Dissolution; In vitro; Blood; Matrix tablet; Blood plasma; Paracetamol; Dosage form; Tablet; Aggregate; Pharmacokinetics; Saliva; Release; Physicochemical properties