A Role for miR-145 in Pulmonary Arterial Hypertension: Evidence From Mouse Models and Patient Samples - Caruso, Paola; Dempsie, Yvonne; Stevens, Hannah C.; McDonald, Robert A.; Long, Lu; Lu, Ruifang; White, Kevin; Mair, Kirsty M.; McClure, John D.; Southwood, Mark; Upton, Paul; Xin, Mei; et al. (Circulation research, 2012)
Keywords: Animals; Biological and medical sciences; Disease Models, Animal; Down-Regulation - genetics; Female; Fundamental and applied biological sciences. Psychology; Gene Knock-In Techniques; Humans; Hypertension, Pulmonary - genetics; Hypertension, Pulmonary - pathology; Hypertension, Pulmonary - prevention & control; Lung - pathology; Lung - physiology; Medical sciences; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs - antagonists & inhibitors; MicroRNAs - genetics; MicroRNAs - physiology; Pneumology; Pulmonary hypertension. Acute cor pulmonale. Pulmonary embolism. Pulmonary vascular diseases; Vertebrates: cardiovascular system; Human; molecular biology; Animal model; Oxygen; remodeling; Respiratory disease; Rodentia; Micro RNA; Cardiovascular disease; Smooth muscle; Pulmonary hypertension; smooth muscle cells; Gene silencing; Vertebrata; Mammalia; Mouse; smooth muscle differentiation; Hypoxia; microRNA; Circulatory system; Differentiation