Pathogenesis of liver fibrosis
Liver fibrosis is a major cause of morbidity and mortality worldwide due to chronic viral hepatitis and, more recently, from fatty liver disease associated with obesity. Hepatic stellate cell activation represents a critical event in fibrosis because these cells become the primary source of extracel...
Saved in:
| Published in | Annual review of pathology Vol. 6; p. 425 |
|---|---|
| Main Authors | , |
| Format | Journal Article |
| Language | English |
| Published |
United States
28.02.2011
|
| Subjects | |
| Online Access | Get more information |
Cover
Loading…
| Abstract | Liver fibrosis is a major cause of morbidity and mortality worldwide due to chronic viral hepatitis and, more recently, from fatty liver disease associated with obesity. Hepatic stellate cell activation represents a critical event in fibrosis because these cells become the primary source of extracellular matrix in liver upon injury. Use of cell-culture and animal models has expanded our understanding of the mechanisms underlying stellate cell activation and has shed new light on genetic regulation, the contribution of immune signaling, and the potential reversibility of the disease. As pathways of fibrogenesis are increasingly clarified, the key challenge will be translating new advances into the development of antifibrotic therapies for patients with chronic liver disease. |
|---|---|
| AbstractList | Liver fibrosis is a major cause of morbidity and mortality worldwide due to chronic viral hepatitis and, more recently, from fatty liver disease associated with obesity. Hepatic stellate cell activation represents a critical event in fibrosis because these cells become the primary source of extracellular matrix in liver upon injury. Use of cell-culture and animal models has expanded our understanding of the mechanisms underlying stellate cell activation and has shed new light on genetic regulation, the contribution of immune signaling, and the potential reversibility of the disease. As pathways of fibrogenesis are increasingly clarified, the key challenge will be translating new advances into the development of antifibrotic therapies for patients with chronic liver disease. |
| Author | Hernandez-Gea, Virginia Friedman, Scott L |
| Author_xml | – sequence: 1 givenname: Virginia surname: Hernandez-Gea fullname: Hernandez-Gea, Virginia organization: Mount Sinai School of Medicine, New York, New York 10029, USA – sequence: 2 givenname: Scott L surname: Friedman fullname: Friedman, Scott L |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/21073339$$D View this record in MEDLINE/PubMed |
| BookMark | eNo1jktLw0AUhQdR7EP_QsnC7ei9M3MnN0spvqBgF3VdJpMbjaSTkLQF_70V9WwOfHA-zkydpy6JUjcIt4jO34WUDoMcdR_2H12rAU8BjRaM82dqikRWO0A3UbNx_ARw1jNfqolByK21xVQt1j_Td0kyNmPW1VnbHGXI6qYcuhO5Uhd1aEe5_uu5ent82Cyf9er16WV5v9LRMu91zD2xseyJ2HvxBjC6XJCKEJny2nJF1gXvKyrr4BhKgooLJ0yRhdHM1eLX2x_KnVTbfmh2Yfja_h8136tCQmw |
| CitedBy_id | crossref_primary_10_1177_1535370219898141 crossref_primary_10_1002_iub_1884 crossref_primary_10_1016_j_jsbmb_2021_106022 crossref_primary_10_1002_jcp_29037 crossref_primary_10_1016_j_ijbiomac_2024_130502 crossref_primary_10_3390_antiox11081437 crossref_primary_10_1038_s41419_018_1032_9 crossref_primary_10_1039_D1FO02545G crossref_primary_10_3390_cells9020290 crossref_primary_10_1016_j_bbagen_2014_10_014 crossref_primary_10_1016_j_jceh_2023_08_015 crossref_primary_10_1002_jmri_27197 crossref_primary_10_1139_cjpp_2016_0157 crossref_primary_10_1038_s41374_018_0133_5 crossref_primary_10_1152_ajpgi_00015_2012 crossref_primary_10_1016_j_jep_2018_11_027 crossref_primary_10_1016_j_phymed_2020_153180 crossref_primary_10_1038_srep37717 crossref_primary_10_1186_s43066_021_00076_w crossref_primary_10_1136_bmjgast_2023_001148 crossref_primary_10_1038_nrgastro_2014_17 crossref_primary_10_1139_bcb_2014_0036 crossref_primary_10_1038_srep33593 crossref_primary_10_1039_D3CC01096A crossref_primary_10_1016_j_taap_2019_114760 crossref_primary_10_1039_C9FO01010F crossref_primary_10_1016_j_surge_2011_11_002 crossref_primary_10_1186_s13578_022_00789_4 crossref_primary_10_3350_cmh_2015_21_1_22 crossref_primary_10_1016_j_jcmgh_2018_09_005 crossref_primary_10_1186_s12876_016_0423_6 crossref_primary_10_1515_amb_2017_0009 crossref_primary_10_3390_cells13090765 crossref_primary_10_1016_j_trsl_2015_10_008 crossref_primary_10_1186_1472_6882_12_51 crossref_primary_10_3389_fphys_2021_801340 crossref_primary_10_1080_08941939_2016_1257666 crossref_primary_10_3748_wjg_v20_i40_14778 crossref_primary_10_1111_bcpt_12844 crossref_primary_10_1186_s13287_022_03041_5 crossref_primary_10_1007_s12072_022_10404_w crossref_primary_10_1080_15376516_2020_1801926 crossref_primary_10_1016_j_lfs_2019_117096 crossref_primary_10_1002_jcb_23342 crossref_primary_10_1002_cbin_10228 crossref_primary_10_3390_ijms22095038 crossref_primary_10_1021_acsabm_1c00130 crossref_primary_10_1038_s41575_020_0266_z crossref_primary_10_1016_j_taap_2017_01_005 crossref_primary_10_1016_j_ejphar_2018_05_030 crossref_primary_10_1371_journal_pone_0145512 crossref_primary_10_1016_j_jff_2018_02_010 crossref_primary_10_1111_bph_13701 crossref_primary_10_3389_fphar_2022_1050093 crossref_primary_10_1007_s00261_021_03300_8 crossref_primary_10_1038_s41577_020_00456_0 crossref_primary_10_1039_C6RA17459K crossref_primary_10_1111_j_1872_034X_2012_01086_x crossref_primary_10_1016_j_ijbiomac_2024_130712 crossref_primary_10_3892_ijmm_2023_5243 crossref_primary_10_1097_CM9_0000000000000835 crossref_primary_10_1126_science_aay0542 crossref_primary_10_1016_j_biopha_2020_110960 crossref_primary_10_1016_j_jid_2021_10_025 crossref_primary_10_1080_08923973_2016_1263860 crossref_primary_10_3390_ijms22041869 crossref_primary_10_3892_etm_2018_6966 crossref_primary_10_3389_fphar_2018_00709 crossref_primary_10_1155_2018_4545321 crossref_primary_10_3390_diseases7030051 crossref_primary_10_1016_j_ejphar_2024_176629 crossref_primary_10_1016_j_apsb_2022_04_010 crossref_primary_10_1016_j_ecoenv_2018_08_050 crossref_primary_10_3390_biomedicines11041090 crossref_primary_10_1021_acs_jafc_8b05179 crossref_primary_10_1016_j_snb_2015_09_041 crossref_primary_10_1016_j_ejcb_2011_09_006 crossref_primary_10_1002_jcp_24801 crossref_primary_10_1016_j_phrs_2023_106886 crossref_primary_10_1016_j_biopha_2017_08_037 crossref_primary_10_3748_wjg_v26_i41_6304 crossref_primary_10_1155_2021_2791142 crossref_primary_10_1038_srep37509 crossref_primary_10_1080_10985549_2023_2205344 crossref_primary_10_3109_15376516_2015_1124956 crossref_primary_10_3390_microorganisms10091769 crossref_primary_10_1016_j_ecoenv_2023_114897 crossref_primary_10_2217_epi_2023_0146 crossref_primary_10_1038_gt_2013_41 crossref_primary_10_1007_s10059_012_0183_2 crossref_primary_10_17795_jjnpp_40285 crossref_primary_10_1016_j_intimp_2016_12_017 crossref_primary_10_1124_jpet_118_256156 crossref_primary_10_1080_01913123_2023_2278627 crossref_primary_10_1016_j_jep_2020_112714 crossref_primary_10_3389_fendo_2021_767785 crossref_primary_10_1155_2016_1068528 crossref_primary_10_1016_j_omtn_2020_07_013 crossref_primary_10_3892_etm_2019_7207 crossref_primary_10_1172_JCI66904 crossref_primary_10_1371_journal_pone_0075361 crossref_primary_10_1039_D1BM00100K crossref_primary_10_1177_1536012119871455 crossref_primary_10_1016_j_intimp_2014_02_006 crossref_primary_10_1016_j_taap_2013_08_009 crossref_primary_10_3390_pathogens11030289 crossref_primary_10_1007_s00535_016_1190_4 crossref_primary_10_1002_nbm_3956 crossref_primary_10_1016_j_cyto_2015_12_007 crossref_primary_10_1016_j_snb_2015_08_064 crossref_primary_10_1080_19490976_2021_1972746 crossref_primary_10_3389_fimmu_2024_1404891 crossref_primary_10_3389_fphar_2024_1396834 crossref_primary_10_3389_fphar_2021_677810 crossref_primary_10_1002_edm2_296 crossref_primary_10_1007_s11655_019_3039_1 crossref_primary_10_3389_fmicb_2024_1342356 crossref_primary_10_1172_JCI96324 crossref_primary_10_1016_j_jhep_2013_06_026 crossref_primary_10_3389_fmolb_2023_1183808 crossref_primary_10_3389_fnut_2021_715183 crossref_primary_10_1016_j_intimp_2018_09_021 crossref_primary_10_1111_jcmm_12542 crossref_primary_10_1016_j_ejphar_2021_174604 crossref_primary_10_1016_j_lfs_2020_117595 crossref_primary_10_1016_j_intimp_2023_111132 crossref_primary_10_1152_ajpgi_00525_2011 crossref_primary_10_1186_s12864_022_08450_7 crossref_primary_10_1371_journal_pone_0092925 crossref_primary_10_1111_bph_14831 crossref_primary_10_1002_jcb_25776 crossref_primary_10_1038_srep11734 crossref_primary_10_4049_jimmunol_2100763 crossref_primary_10_1016_j_biopha_2020_109932 crossref_primary_10_3748_wjg_v26_i11_1113 crossref_primary_10_1007_s00281_022_00917_9 crossref_primary_10_1007_s12668_017_0494_z crossref_primary_10_1038_s41420_023_01347_8 crossref_primary_10_1021_acs_jafc_6b03700 crossref_primary_10_1016_j_ejphar_2021_173982 crossref_primary_10_1038_nrgastro_2016_16 crossref_primary_10_1016_j_molimm_2017_10_006 crossref_primary_10_3390_cells8121556 crossref_primary_10_1002_jcb_24458 crossref_primary_10_1002_hep_25817 crossref_primary_10_13105_wjma_v9_i2_108 crossref_primary_10_1016_j_sjbs_2020_10_063 crossref_primary_10_1111_prd_12030 crossref_primary_10_4254_wjh_v8_i4_211 crossref_primary_10_3390_nu14050962 crossref_primary_10_3892_etm_2016_3135 crossref_primary_10_1155_2015_248920 crossref_primary_10_1016_j_gendis_2022_08_013 crossref_primary_10_3390_ijms21093267 crossref_primary_10_1016_j_dld_2020_11_035 crossref_primary_10_1111_jcmm_14543 crossref_primary_10_1586_egh_11_92 crossref_primary_10_1371_journal_pone_0108505 crossref_primary_10_3390_ijerph17113802 crossref_primary_10_1016_j_ijbiomac_2022_05_041 crossref_primary_10_1515_almed_2023_0172 crossref_primary_10_1111_liv_12371 crossref_primary_10_1002_hep_26916 crossref_primary_10_1016_j_cbi_2023_110626 crossref_primary_10_3892_mmr_2018_8516 crossref_primary_10_1159_000366206 crossref_primary_10_1016_j_jbiomech_2023_111504 crossref_primary_10_3389_fimmu_2022_841314 crossref_primary_10_1016_j_canlet_2018_01_055 crossref_primary_10_1371_journal_pone_0104397 crossref_primary_10_1038_s41467_023_38371_2 crossref_primary_10_1016_j_phymed_2023_155145 crossref_primary_10_1002_tox_23458 crossref_primary_10_1002_hep_24500 crossref_primary_10_1101_sqb_2015_80_027185 crossref_primary_10_1158_1541_7786_MCR_14_0542 crossref_primary_10_3389_fphar_2018_00525 crossref_primary_10_1007_s00247_011_2143_y crossref_primary_10_1002_iub_1492 crossref_primary_10_3389_fphar_2018_00762 crossref_primary_10_18632_oncotarget_15472 crossref_primary_10_1152_ajpendo_00285_2016 crossref_primary_10_3748_wjg_v28_i1_123 crossref_primary_10_1007_s12011_024_04177_6 crossref_primary_10_3390_nano6010008 crossref_primary_10_1111_liv_12106 crossref_primary_10_1016_j_intimp_2019_105838 crossref_primary_10_1111_imm_13193 crossref_primary_10_1111_liv_15612 crossref_primary_10_3390_microorganisms10051045 crossref_primary_10_1016_j_clinre_2012_05_005 crossref_primary_10_3389_fimmu_2020_578314 crossref_primary_10_1016_j_bcp_2024_116044 crossref_primary_10_1016_j_tox_2016_11_004 crossref_primary_10_3736_jcim20120512 crossref_primary_10_1080_09674845_2017_1362950 crossref_primary_10_1016_j_jnutbio_2022_109039 crossref_primary_10_1155_2019_5376165 crossref_primary_10_3389_fphar_2018_00553 crossref_primary_10_1016_j_jhep_2014_04_043 crossref_primary_10_1136_gutjnl_2021_325150 crossref_primary_10_1016_j_clinre_2011_01_011 crossref_primary_10_3390_biology12081087 crossref_primary_10_1111_hepr_13182 crossref_primary_10_1186_s13071_021_04663_z crossref_primary_10_1074_jbc_M115_671735 crossref_primary_10_1016_j_actbio_2021_04_020 crossref_primary_10_1016_j_lfs_2021_119884 crossref_primary_10_1042_BSR20160111 crossref_primary_10_6061_clinics_2016_06_07 crossref_primary_10_3390_cells8121503 crossref_primary_10_1038_s41419_022_04789_7 crossref_primary_10_1016_j_jnutbio_2022_109020 crossref_primary_10_1016_j_joim_2020_03_001 crossref_primary_10_1016_j_heliyon_2024_e27076 crossref_primary_10_1016_j_ejphar_2022_174770 crossref_primary_10_1016_j_biomaterials_2019_119616 crossref_primary_10_1016_j_bbadis_2018_12_018 crossref_primary_10_1038_s41598_018_36189_3 crossref_primary_10_1007_s40139_015_0091_1 crossref_primary_10_1080_08923973_2022_2128369 crossref_primary_10_1126_scitranslmed_3003205 crossref_primary_10_1038_s41598_018_31599_9 crossref_primary_10_1186_s12885_019_6397_3 crossref_primary_10_1002_jmri_25657 crossref_primary_10_1016_j_bbadis_2013_06_001 crossref_primary_10_1186_1742_6405_10_29 crossref_primary_10_2217_fon_15_39 crossref_primary_10_1016_j_metop_2022_100179 crossref_primary_10_1007_s11010_020_03691_0 crossref_primary_10_1016_j_canlet_2022_216048 crossref_primary_10_1016_j_intimp_2017_10_019 crossref_primary_10_1038_s41419_021_04403_2 crossref_primary_10_1038_s41598_022_25738_6 crossref_primary_10_15252_emmm_201404527 crossref_primary_10_1016_j_ymthe_2018_08_016 crossref_primary_10_3892_etm_2017_4956 crossref_primary_10_1016_j_biopha_2018_10_005 crossref_primary_10_1038_mt_2013_181 crossref_primary_10_14202_vetworld_2018_627_635 crossref_primary_10_3390_ijms17050681 crossref_primary_10_3390_nu10081057 crossref_primary_10_14218_JCTH_2021_00101 crossref_primary_10_1002_fsn3_2668 crossref_primary_10_1111_jgh_12641 crossref_primary_10_1093_infdis_jis926 crossref_primary_10_1016_j_cbi_2014_06_017 crossref_primary_10_1038_s41467_022_34993_0 crossref_primary_10_5812_hepatmon_113968 crossref_primary_10_1007_s13770_020_00267_3 crossref_primary_10_1016_j_prp_2021_153367 crossref_primary_10_1002_cam4_5740 crossref_primary_10_1002_jcb_29520 crossref_primary_10_1155_2021_6651839 crossref_primary_10_3923_ijp_2019_418_427 crossref_primary_10_3389_fimmu_2017_01461 crossref_primary_10_1371_journal_pone_0070744 crossref_primary_10_1016_j_yexcr_2017_08_001 crossref_primary_10_3390_cells9040929 crossref_primary_10_1016_j_etap_2016_05_033 crossref_primary_10_1177_2040622321993442 crossref_primary_10_1016_j_jep_2013_03_067 crossref_primary_10_18632_oncotarget_17453 crossref_primary_10_1016_j_amjms_2017_04_011 crossref_primary_10_1172_JCI74382 crossref_primary_10_17826_cumj_365057 crossref_primary_10_3748_wjg_v26_i28_4094 crossref_primary_10_3390_ijms25094749 crossref_primary_10_1016_j_ebiom_2017_08_016 crossref_primary_10_1016_j_reth_2021_11_005 crossref_primary_10_1111_liv_15893 crossref_primary_10_3389_fimmu_2020_00148 crossref_primary_10_1016_j_cyto_2018_11_003 crossref_primary_10_3168_jds_2022_22021 crossref_primary_10_1002_hep_25649 crossref_primary_10_25298_2616_5546_2020_4_1_45_54 crossref_primary_10_1080_14728222_2019_1559823 crossref_primary_10_1096_fj_201902307RRR crossref_primary_10_3390_cancers16050901 crossref_primary_10_1016_j_toxlet_2018_03_010 crossref_primary_10_1007_s40265_020_01458_x crossref_primary_10_1016_j_ijbiomac_2023_125540 crossref_primary_10_1002_jbt_23648 crossref_primary_10_1002_jmri_25425 crossref_primary_10_3748_wjg_v21_i3_878 crossref_primary_10_1080_15384101_2021_1897241 crossref_primary_10_1155_2015_954548 crossref_primary_10_1007_s13770_020_00245_9 crossref_primary_10_3350_cmh_2014_20_3_228 crossref_primary_10_1097_RLI_0000000000001084 crossref_primary_10_1016_j_clinre_2011_02_012 crossref_primary_10_1002_lipd_12157 crossref_primary_10_1152_ajpgi_00040_2019 crossref_primary_10_1111_jcmm_13002 crossref_primary_10_1016_j_actbio_2021_11_015 crossref_primary_10_1074_jbc_REV120_011356 crossref_primary_10_1186_s11658_018_0098_9 crossref_primary_10_3389_fphar_2022_787748 crossref_primary_10_3390_ijms18071447 crossref_primary_10_1038_s12276_018_0199_6 crossref_primary_10_1007_s13659_014_0050_2 crossref_primary_10_3390_antiox8080277 crossref_primary_10_1016_j_cell_2013_03_028 crossref_primary_10_1080_01480545_2024_2358066 crossref_primary_10_1016_j_ebiom_2019_03_058 crossref_primary_10_1016_j_cell_2013_03_026 crossref_primary_10_1016_j_taap_2016_07_003 crossref_primary_10_1620_tjem_229_35 crossref_primary_10_1096_fj_12_214189 crossref_primary_10_1111_exd_15054 crossref_primary_10_1016_j_ejrad_2020_108857 crossref_primary_10_1016_j_jpba_2024_116204 crossref_primary_10_1021_acsnano_1c10534 crossref_primary_10_1016_j_tem_2015_01_002 crossref_primary_10_3748_wjg_v26_i47_7513 crossref_primary_10_3390_ijms21134737 crossref_primary_10_5966_sctm_2015_0265 crossref_primary_10_1002_hep_26763 crossref_primary_10_1002_SMMD_20220010 crossref_primary_10_1002_poh2_11 crossref_primary_10_3390_genes11070729 crossref_primary_10_3892_mmr_2015_4497 crossref_primary_10_1101_gad_238246_114 crossref_primary_10_3892_etm_2019_8047 crossref_primary_10_1016_j_yexcr_2018_02_003 crossref_primary_10_1016_j_cellsig_2023_110752 crossref_primary_10_1021_acs_jnatprod_5b00814 crossref_primary_10_1111_imr_12063 crossref_primary_10_1016_j_bbrc_2019_07_015 crossref_primary_10_1016_j_jconrel_2023_05_002 crossref_primary_10_3389_fphar_2023_1101703 crossref_primary_10_1038_s41598_018_37516_4 crossref_primary_10_1038_srep08812 crossref_primary_10_1016_j_biochi_2015_06_016 crossref_primary_10_1002_path_5856 crossref_primary_10_1002_mrm_25341 crossref_primary_10_1016_j_bbadis_2019_03_002 crossref_primary_10_1016_j_arcmed_2023_102937 crossref_primary_10_1038_jhg_2017_75 crossref_primary_10_3727_105221616X693891 crossref_primary_10_3389_fphar_2017_00976 crossref_primary_10_1093_abbs_gmz129 crossref_primary_10_1097_QAD_0000000000000975 crossref_primary_10_1007_s11427_019_1761_1 crossref_primary_10_1111_acer_12167 crossref_primary_10_1007_s00261_021_03396_y crossref_primary_10_1021_acsami_8b10527 crossref_primary_10_1016_j_cbi_2019_05_041 crossref_primary_10_3390_ijms18030553 crossref_primary_10_1002_ptr_7569 crossref_primary_10_1016_j_immuni_2022_08_002 crossref_primary_10_3389_fcell_2020_00176 crossref_primary_10_18632_oncotarget_17134 crossref_primary_10_1007_s10517_017_3608_2 crossref_primary_10_1515_med_2024_0945 crossref_primary_10_3390_cells12030378 crossref_primary_10_1007_s11655_021_3304_y crossref_primary_10_1016_j_semcdb_2019_10_015 crossref_primary_10_1038_srep17762 crossref_primary_10_1186_s13020_021_00489_0 crossref_primary_10_1007_s11604_020_01020_5 crossref_primary_10_1016_j_omtn_2018_04_016 crossref_primary_10_30565_medalanya_775667 crossref_primary_10_3389_fimmu_2017_01195 crossref_primary_10_1136_jitc_2020_001945 crossref_primary_10_3390_v12080815 crossref_primary_10_1371_journal_pone_0101179 crossref_primary_10_3390_cells10102530 crossref_primary_10_3748_wjg_v23_i11_2002 crossref_primary_10_1148_radiol_2015142141 crossref_primary_10_1007_s10620_016_4075_8 crossref_primary_10_1007_s00330_020_07235_4 crossref_primary_10_1111_jpi_12271 crossref_primary_10_18632_oncotarget_6447 crossref_primary_10_3390_molecules19033327 crossref_primary_10_1039_C8FO02369G crossref_primary_10_1016_j_intimp_2023_110530 crossref_primary_10_1111_j_1440_1746_2011_06940_x crossref_primary_10_1146_annurev_nutr_072610_145138 crossref_primary_10_1016_j_jhep_2012_09_007 crossref_primary_10_1186_s13027_018_0183_8 crossref_primary_10_3748_wjg_v21_i27_8326 crossref_primary_10_1111_jcmm_17884 crossref_primary_10_1016_j_ejphar_2021_174198 crossref_primary_10_1155_2016_7478650 crossref_primary_10_5021_ad_2019_31_4_365 crossref_primary_10_1016_j_ajpath_2016_09_001 crossref_primary_10_1111_imr_12279 crossref_primary_10_1038_s41419_021_04263_w crossref_primary_10_1016_j_intimp_2017_12_023 crossref_primary_10_1016_j_taap_2016_12_002 crossref_primary_10_1016_j_jep_2023_117516 crossref_primary_10_1172_JCI92823 crossref_primary_10_1242_dmm_038810 crossref_primary_10_1016_j_ecoenv_2024_116142 crossref_primary_10_1016_j_biopha_2018_02_091 crossref_primary_10_3748_wjg_v26_i2_109 crossref_primary_10_1089_scd_2023_0110 crossref_primary_10_1155_2021_6890423 crossref_primary_10_1016_j_yexmp_2014_04_003 crossref_primary_10_1097_RCT_0000000000001631 crossref_primary_10_1042_CS20160334 crossref_primary_10_1016_j_jceh_2018_02_001 crossref_primary_10_1016_j_jcmgh_2022_08_001 crossref_primary_10_3892_mmr_2019_10881 crossref_primary_10_1038_ctg_2017_25 crossref_primary_10_1148_radiol_212325 crossref_primary_10_1002_jmri_25132 crossref_primary_10_1177_1535370217701005 crossref_primary_10_1016_j_cbi_2014_04_016 crossref_primary_10_1186_s13020_022_00607_6 crossref_primary_10_1007_s10495_012_0791_5 crossref_primary_10_1097_RLI_0000000000000952 crossref_primary_10_18632_oncotarget_6466 crossref_primary_10_1016_j_ajg_2021_12_003 crossref_primary_10_1016_j_yexcr_2018_03_015 crossref_primary_10_1016_j_taap_2015_03_022 crossref_primary_10_3389_fcell_2019_00245 crossref_primary_10_1016_j_mce_2013_09_020 crossref_primary_10_1142_S0192415X22500938 crossref_primary_10_3390_app10175941 crossref_primary_10_1038_nm_2848 crossref_primary_10_1073_pnas_1821045116 crossref_primary_10_5005_jp_journals_10018_1370 crossref_primary_10_1016_j_lfs_2024_122542 crossref_primary_10_1111_bph_15490 crossref_primary_10_3390_ijms24043386 crossref_primary_10_1002_hep_28766 crossref_primary_10_1089_vim_2018_0018 crossref_primary_10_1038_ncomms13817 crossref_primary_10_1097_MD_0000000000013287 crossref_primary_10_2147_DDDT_S412818 crossref_primary_10_1111_1751_2980_12791 crossref_primary_10_1172_JCI98156 crossref_primary_10_1016_j_surg_2017_04_013 crossref_primary_10_1080_11263504_2020_1852329 crossref_primary_10_1371_journal_pone_0150978 crossref_primary_10_18632_oncotarget_19376 crossref_primary_10_1021_acsomega_3c07126 crossref_primary_10_1039_C7FO00700K crossref_primary_10_1155_2018_5360496 crossref_primary_10_3390_ijms20071634 crossref_primary_10_1002_path_4104 crossref_primary_10_1186_s12964_018_0306_2 crossref_primary_10_3389_fphar_2017_00514 crossref_primary_10_1097_JBR_0000000000000026 crossref_primary_10_1371_journal_pone_0197117 crossref_primary_10_3389_fphar_2015_00300 crossref_primary_10_3390_molecules25184310 crossref_primary_10_3390_ijms141020543 crossref_primary_10_1002_ptr_6410 crossref_primary_10_1136_postgradmedj_2013_131883 crossref_primary_10_3389_fimmu_2021_760199 crossref_primary_10_18632_oncotarget_22539 crossref_primary_10_1016_j_jhep_2024_01_027 crossref_primary_10_1016_j_scitotenv_2020_139920 crossref_primary_10_1016_j_csbj_2020_11_038 crossref_primary_10_1111_cpr_13500 crossref_primary_10_1371_journal_pone_0095462 crossref_primary_10_1002_path_4119 crossref_primary_10_1007_s10753_013_9643_x crossref_primary_10_1016_j_jhep_2015_01_003 crossref_primary_10_1016_j_jnutbio_2016_11_003 crossref_primary_10_1002_jmri_28208 crossref_primary_10_1371_journal_pone_0083481 crossref_primary_10_1002_hep_29627 crossref_primary_10_1053_j_gastro_2012_04_031 crossref_primary_10_1038_tpj_2017_17 crossref_primary_10_3390_ijms23020627 crossref_primary_10_1016_j_intimp_2020_107331 crossref_primary_10_1016_j_matbio_2018_01_020 crossref_primary_10_1016_j_jhep_2016_11_003 crossref_primary_10_1016_j_jhep_2012_07_042 crossref_primary_10_1016_j_ejphar_2020_173424 crossref_primary_10_1007_s10753_017_0528_2 crossref_primary_10_1007_s40265_016_0546_7 crossref_primary_10_3892_ijmm_2016_2692 crossref_primary_10_1139_bcb_2021_0585 crossref_primary_10_1177_1535370213480698 crossref_primary_10_1007_s12072_013_9439_y crossref_primary_10_4254_wjh_v8_i32_1354 crossref_primary_10_1016_j_biocel_2011_10_011 crossref_primary_10_1016_j_intimp_2016_07_028 crossref_primary_10_1039_D3TB02766J crossref_primary_10_1038_nbt_4231 crossref_primary_10_3892_mmr_2017_7044 crossref_primary_10_1016_j_jtemb_2022_127102 crossref_primary_10_1016_j_phymed_2022_154587 crossref_primary_10_1016_j_cbi_2018_08_016 crossref_primary_10_1016_j_phrs_2012_07_003 crossref_primary_10_3892_mmr_2018_9397 crossref_primary_10_12968_gasn_2016_14_Sup5_S12 crossref_primary_10_1016_j_etap_2017_02_012 crossref_primary_10_3389_fimmu_2021_625472 crossref_primary_10_3892_mmr_2014_3019 crossref_primary_10_1016_j_acra_2021_07_005 crossref_primary_10_3390_bioengineering10010017 crossref_primary_10_3390_ijms20081885 crossref_primary_10_1080_2162402X_2020_1725355 crossref_primary_10_1016_j_livres_2017_05_003 crossref_primary_10_1016_j_cbi_2011_07_001 crossref_primary_10_1111_jgh_12147 crossref_primary_10_1042_CS20201111 crossref_primary_10_1002_jcb_29380 crossref_primary_10_1016_j_biopha_2022_114173 crossref_primary_10_1053_j_gastro_2014_07_044 crossref_primary_10_1016_j_fitote_2014_10_009 crossref_primary_10_1016_j_biopha_2016_11_066 crossref_primary_10_1007_s12602_020_09663_6 crossref_primary_10_3390_molecules23071705 crossref_primary_10_3727_105221614X13919976902057 crossref_primary_10_3727_105221619X15486875608177 crossref_primary_10_1097_QAD_0000000000001203 crossref_primary_10_1111_bph_12323 crossref_primary_10_1186_s13063_016_1454_6 crossref_primary_10_22416_1382_4376_2016_26_3_52_63 crossref_primary_10_1016_j_intimp_2022_109034 crossref_primary_10_1080_09168451_2017_1308242 crossref_primary_10_26565_2617_409X_2021_7_06 crossref_primary_10_1016_j_biopha_2023_114220 crossref_primary_10_1007_s40139_015_0088_9 crossref_primary_10_1038_s41598_020_60615_0 crossref_primary_10_1111_bph_12114 crossref_primary_10_2139_ssrn_3763765 crossref_primary_10_3748_wjg_v22_i9_2779 crossref_primary_10_3389_fphar_2023_1234300 crossref_primary_10_1002_hep_31987 crossref_primary_10_1186_s40199_015_0135_4 crossref_primary_10_3389_fphar_2017_00929 crossref_primary_10_1038_srep30957 crossref_primary_10_3390_jpm12111812 crossref_primary_10_1002_jmri_27391 crossref_primary_10_1111_hepr_12352 crossref_primary_10_3748_wjg_v23_i13_2330 crossref_primary_10_3390_cancers15030632 crossref_primary_10_1002_biof_1432 crossref_primary_10_37015_AUDT_2019_190815 crossref_primary_10_3390_cells9030568 crossref_primary_10_1097_HEP_0000000000000182 crossref_primary_10_1007_s10528_024_10684_x crossref_primary_10_1016_j_intimp_2023_110550 crossref_primary_10_1111_hepr_12356 crossref_primary_10_1053_j_gastro_2011_08_008 crossref_primary_10_1093_alcalc_agaa085 crossref_primary_10_1371_journal_pone_0064992 crossref_primary_10_1016_j_intimp_2019_05_055 crossref_primary_10_1152_ajpgi_00453_2020 crossref_primary_10_1021_acs_jproteome_8b00379 crossref_primary_10_1109_LRA_2022_3144766 crossref_primary_10_3892_etm_2022_11474 crossref_primary_10_3390_nu15173740 crossref_primary_10_1002_hep_31752 crossref_primary_10_1016_j_prostaglandins_2017_08_008 crossref_primary_10_1371_journal_pone_0109254 crossref_primary_10_1074_jbc_M116_744631 crossref_primary_10_1016_j_clnu_2015_10_015 crossref_primary_10_1038_srep36037 crossref_primary_10_1159_000516892 crossref_primary_10_1016_j_ijpharm_2022_122063 crossref_primary_10_3389_fmed_2020_00130 crossref_primary_10_1007_s12275_016_6240_3 crossref_primary_10_1038_s41598_022_18123_w crossref_primary_10_1038_cmi_2011_53 crossref_primary_10_1152_ajpgi_00257_2015 crossref_primary_10_3390_cells11223579 crossref_primary_10_1002_hep_31780 crossref_primary_10_3892_ijo_2015_3024 crossref_primary_10_1002_hep_27285 crossref_primary_10_3892_mmr_2017_6161 crossref_primary_10_1016_S1875_5364_16_30025_5 crossref_primary_10_3390_cancers15041308 crossref_primary_10_1016_j_taap_2014_08_006 crossref_primary_10_3389_fcell_2021_716209 crossref_primary_10_3390_biomedicines9081014 crossref_primary_10_1007_s10620_015_3976_2 crossref_primary_10_1016_S2468_1253_16_30110_8 crossref_primary_10_1016_j_pharmthera_2020_107791 crossref_primary_10_1002_jcp_26469 crossref_primary_10_1172_JCI93558 crossref_primary_10_1007_s13273_021_00196_9 crossref_primary_10_1016_j_lfs_2017_11_050 crossref_primary_10_1007_s10620_015_3585_0 crossref_primary_10_1155_2016_8762345 crossref_primary_10_3389_fphar_2023_1124015 crossref_primary_10_1016_j_envpol_2023_121388 crossref_primary_10_1016_j_trsl_2019_02_005 crossref_primary_10_1155_2022_5063088 crossref_primary_10_1364_BOE_7_005081 crossref_primary_10_1371_journal_pone_0090608 crossref_primary_10_1002_jemt_23554 crossref_primary_10_1016_j_jhep_2015_11_019 crossref_primary_10_1139_cjpp_2015_0437 crossref_primary_10_1016_j_jnutbio_2017_11_003 crossref_primary_10_1111_liv_13177 crossref_primary_10_1007_s12033_023_01030_4 crossref_primary_10_3390_molecules191118767 crossref_primary_10_1007_s10517_016_3468_1 crossref_primary_10_1007_s13277_015_3501_4 crossref_primary_10_3390_ijms241512509 crossref_primary_10_1038_s41467_023_35941_2 crossref_primary_10_1016_S1875_5364_21_60018_3 crossref_primary_10_3389_fendo_2024_1359960 crossref_primary_10_1016_j_cbi_2016_11_022 crossref_primary_10_1177_0960327115578864 crossref_primary_10_1242_dmm_014050 crossref_primary_10_1073_pnas_1506113113 crossref_primary_10_1152_ajpgi_00415_2011 crossref_primary_10_1016_j_intimp_2017_06_001 crossref_primary_10_1111_jcmm_13501 crossref_primary_10_5009_gnl15226 crossref_primary_10_14336_AD_2023_0830 crossref_primary_10_1080_13880209_2021_1999275 crossref_primary_10_1016_j_matbio_2015_01_004 crossref_primary_10_1155_2017_2670658 crossref_primary_10_1016_j_jddst_2021_102883 crossref_primary_10_1007_s10735_020_09868_7 crossref_primary_10_1016_j_jhep_2014_09_033 crossref_primary_10_3389_fphar_2022_1057829 crossref_primary_10_1371_journal_pone_0187065 crossref_primary_10_1016_j_jhep_2015_11_020 crossref_primary_10_1186_s12859_022_05030_0 crossref_primary_10_1002_hep_32640 crossref_primary_10_1016_j_biomaterials_2020_120538 crossref_primary_10_1242_jcs_202317 crossref_primary_10_1016_j_jhep_2020_06_020 crossref_primary_10_1088_1742_6596_1073_3_032076 crossref_primary_10_3390_cells8111419 crossref_primary_10_1016_j_phymed_2020_153294 crossref_primary_10_14218_JCTH_2018_00053 crossref_primary_10_1128_MCB_00049_13 crossref_primary_10_1371_journal_pone_0167658 crossref_primary_10_1371_journal_pone_0108005 crossref_primary_10_1038_srep35426 crossref_primary_10_1293_tox_2020_0033 crossref_primary_10_1016_j_addr_2017_07_014 crossref_primary_10_1080_15569543_2023_2191263 crossref_primary_10_1016_j_bbadis_2016_09_001 crossref_primary_10_1016_j_bbrc_2019_03_156 crossref_primary_10_1016_j_biopha_2017_10_065 crossref_primary_10_1016_j_taap_2018_11_011 crossref_primary_10_1016_j_etap_2015_12_018 crossref_primary_10_3389_fimmu_2021_749646 crossref_primary_10_1016_j_phrs_2021_105926 crossref_primary_10_1038_mt_2016_127 crossref_primary_10_1016_j_jnutbio_2019_06_001 crossref_primary_10_1007_s40139_013_0020_0 crossref_primary_10_1016_j_aohep_2021_100341 crossref_primary_10_1016_j_cmet_2019_10_014 crossref_primary_10_1073_pnas_1419119111 crossref_primary_10_1177_0284185120917117 crossref_primary_10_1016_j_dld_2021_11_002 crossref_primary_10_1002_cbin_11206 crossref_primary_10_1111_j_1365_2893_2011_01561_x crossref_primary_10_1007_s10565_022_09714_4 crossref_primary_10_1039_C7RA10847H crossref_primary_10_1016_j_tox_2024_153829 crossref_primary_10_1038_srep18038 crossref_primary_10_1371_journal_pone_0065897 crossref_primary_10_3389_fimmu_2023_1237042 crossref_primary_10_1016_j_biochi_2015_03_015 crossref_primary_10_1016_j_mce_2019_110538 crossref_primary_10_1016_j_clinbiochem_2022_12_012 crossref_primary_10_1016_j_freeradbiomed_2020_11_014 crossref_primary_10_1038_s41419_018_1068_x crossref_primary_10_1038_s41598_019_51189_7 crossref_primary_10_3390_cells12172127 crossref_primary_10_1007_s43152_021_00030_3 crossref_primary_10_3390_molecules22050754 crossref_primary_10_1016_j_jhep_2014_08_013 crossref_primary_10_36740_WLek202005120 crossref_primary_10_1016_j_ajme_2017_06_007 crossref_primary_10_1096_fj_202000494RR crossref_primary_10_1155_2012_734987 crossref_primary_10_1590_0037_8682_0302_2016 crossref_primary_10_1016_S2210_7401_11_70002_X crossref_primary_10_1038_s41420_018_0095_9 crossref_primary_10_12677_ACM_2023_1371562 crossref_primary_10_1002_hep_29275 crossref_primary_10_1016_j_ajpath_2012_06_011 crossref_primary_10_1517_17425247_2012_638625 crossref_primary_10_1016_j_biomaterials_2023_122134 crossref_primary_10_1038_s41419_022_05034_x crossref_primary_10_34133_bmr_0042 crossref_primary_10_1016_j_heliyon_2024_e24558 crossref_primary_10_1016_j_intimp_2024_112442 crossref_primary_10_1038_srep18272 crossref_primary_10_1038_s41388_018_0383_0 crossref_primary_10_1111_febs_12818 crossref_primary_10_1016_j_prp_2024_155275 crossref_primary_10_1139_y2012_125 crossref_primary_10_1016_j_semcdb_2016_01_022 crossref_primary_10_1016_j_bbalip_2012_07_022 crossref_primary_10_1080_08916934_2023_2250101 crossref_primary_10_1586_17474124_2015_1003209 crossref_primary_10_3892_mmr_2015_4618 crossref_primary_10_3389_fphar_2021_676608 crossref_primary_10_5812_jjnpp_113484 crossref_primary_10_1016_j_ccell_2016_09_004 crossref_primary_10_3390_ijms24076737 crossref_primary_10_3389_fgene_2020_594824 crossref_primary_10_18632_oncotarget_27532 crossref_primary_10_1016_j_jep_2013_08_049 crossref_primary_10_7717_peerj_14299 crossref_primary_10_3390_ijms20246314 crossref_primary_10_1016_j_jbc_2021_101331 crossref_primary_10_1016_j_bbrc_2023_04_011 crossref_primary_10_33590_emjhepatol_10313576 crossref_primary_10_1159_000441229 crossref_primary_10_1016_j_taap_2016_01_012 crossref_primary_10_3390_ijms25020975 crossref_primary_10_1016_j_bbrc_2015_11_029 crossref_primary_10_1038_s12276_022_00831_y crossref_primary_10_3390_biology11050637 crossref_primary_10_1007_s11010_021_04182_6 crossref_primary_10_1002_hep_32220 crossref_primary_10_1080_09674845_2019_1600325 crossref_primary_10_1016_j_biopha_2016_06_007 crossref_primary_10_1111_j_1440_1746_2011_07024_x crossref_primary_10_1016_j_clinre_2013_08_014 crossref_primary_10_1016_j_lfs_2023_122221 crossref_primary_10_1111_jgh_14081 crossref_primary_10_3892_etm_2016_3915 crossref_primary_10_1074_jbc_M113_517953 crossref_primary_10_4254_wjh_v4_i10_274 crossref_primary_10_1089_zeb_2012_0821 crossref_primary_10_1111_ajt_13749 crossref_primary_10_1002_adfm_202214059 crossref_primary_10_1016_j_ecoenv_2023_115409 crossref_primary_10_3748_wjg_v23_i32_5904 crossref_primary_10_2217_hep_2017_0026 crossref_primary_10_1002_cbin_10790 crossref_primary_10_1016_j_bcp_2024_116121 crossref_primary_10_1016_j_toxlet_2017_03_013 crossref_primary_10_1088_1758_5090_ad304d crossref_primary_10_3389_fcimb_2019_00423 crossref_primary_10_1016_j_addr_2020_06_026 crossref_primary_10_1016_j_jhep_2015_11_031 crossref_primary_10_1007_s12072_022_10303_0 crossref_primary_10_11603_mcch_2410_681X_2020_v_i1_11052 crossref_primary_10_1016_j_jmii_2021_03_017 crossref_primary_10_3892_etm_2019_7534 crossref_primary_10_18632_oncotarget_3652 crossref_primary_10_1053_j_gastro_2019_07_029 crossref_primary_10_1016_j_apsb_2021_12_016 crossref_primary_10_3892_etm_2019_7548 crossref_primary_10_1038_s41374_018_0178_5 crossref_primary_10_1186_s12967_022_03689_w crossref_primary_10_1111_imr_12626 crossref_primary_10_1111_jfbc_13085 crossref_primary_10_1016_j_jhep_2015_10_007 crossref_primary_10_1016_j_biopha_2021_112298 crossref_primary_10_3389_fphar_2021_656115 crossref_primary_10_1126_sciimmunol_aar7754 crossref_primary_10_1515_almed_2023_0081 crossref_primary_10_1096_fj_201902438R crossref_primary_10_5812_gct_101443 crossref_primary_10_1002_cbdv_202201110 crossref_primary_10_1016_j_mehy_2016_11_014 crossref_primary_10_1016_j_niox_2019_08_004 crossref_primary_10_1016_j_biopha_2017_03_013 crossref_primary_10_1002_ddr_21649 crossref_primary_10_1002_jhbp_245 crossref_primary_10_1128_JVI_03106_14 crossref_primary_10_1186_1755_1536_6_19 crossref_primary_10_1111_jcpe_13682 crossref_primary_10_1016_j_cellsig_2019_01_012 crossref_primary_10_1007_s00261_021_03051_6 crossref_primary_10_1016_j_matbio_2022_06_006 crossref_primary_10_1186_s42826_021_00095_z crossref_primary_10_1016_j_jcmgh_2023_07_009 crossref_primary_10_1080_02652048_2023_2258974 crossref_primary_10_22246_jikm_2021_42_6_1223 crossref_primary_10_1080_00365521_2022_2041085 crossref_primary_10_1093_cei_uxad107 crossref_primary_10_1016_j_cmet_2024_04_020 crossref_primary_10_1016_j_pharmthera_2023_108563 crossref_primary_10_3390_antiox10030384 crossref_primary_10_1097_TP_0000000000001623 crossref_primary_10_1371_journal_pone_0182202 crossref_primary_10_1155_2018_1239143 crossref_primary_10_1016_j_jep_2021_114433 crossref_primary_10_1016_j_toxlet_2020_10_001 crossref_primary_10_1002_jcb_24392 crossref_primary_10_1111_j_1742_7843_2012_00903_x crossref_primary_10_1039_C9NR04902A crossref_primary_10_1177_1091581814566472 crossref_primary_10_2174_0929867330666230209100059 crossref_primary_10_1111_jvh_12213 crossref_primary_10_1002_jcb_28756 crossref_primary_10_1097_MEG_0000000000002059 crossref_primary_10_1016_j_bbrc_2019_05_152 crossref_primary_10_1016_j_biopha_2017_03_007 crossref_primary_10_1016_j_taap_2012_09_016 crossref_primary_10_3892_mmr_2017_6610 crossref_primary_10_1007_s12072_016_9740_7 crossref_primary_10_1186_s13069_016_0042_4 crossref_primary_10_1042_BSR20193385 crossref_primary_10_1016_j_fshw_2020_08_007 crossref_primary_10_1152_ajpgi_00334_2020 crossref_primary_10_2147_DDDT_S467480 crossref_primary_10_1016_j_nucmedbio_2014_11_007 crossref_primary_10_1038_srep43446 crossref_primary_10_1113_EP089328 crossref_primary_10_1016_j_fitote_2024_105974 crossref_primary_10_1177_0960327119891212 crossref_primary_10_1016_j_bbadis_2012_11_017 crossref_primary_10_1038_labinvest_2015_152 crossref_primary_10_1007_s00436_015_4782_7 crossref_primary_10_1002_hep_31167 crossref_primary_10_3892_mmr_2021_12519 crossref_primary_10_1039_C9CS00309F crossref_primary_10_1111_jphp_12283 crossref_primary_10_1016_j_jep_2011_12_028 crossref_primary_10_3389_fphys_2021_666138 crossref_primary_10_1016_j_cellsig_2020_109861 crossref_primary_10_3390_ijms20102507 crossref_primary_10_1111_jcmm_13568 crossref_primary_10_1007_s00261_020_02677_2 crossref_primary_10_1155_2014_869390 crossref_primary_10_3748_wjg_v27_i40_6908 crossref_primary_10_1002_hep_25736 crossref_primary_10_1016_j_jafr_2021_100245 crossref_primary_10_1038_nprot_2015_017 crossref_primary_10_1016_j_metabol_2021_155115 crossref_primary_10_1016_j_phymed_2021_153746 crossref_primary_10_1038_aps_2014_41 crossref_primary_10_1007_s11010_014_2298_6 crossref_primary_10_1038_srep44544 crossref_primary_10_1590_0074_02760140192 crossref_primary_10_3390_ijms242216086 crossref_primary_10_1364_BOE_8_003816 crossref_primary_10_1016_j_stem_2018_05_027 crossref_primary_10_1016_j_cbi_2013_10_008 crossref_primary_10_3892_ijmm_2015_2264 crossref_primary_10_3390_ijms241411606 crossref_primary_10_1111_jcmm_12286 crossref_primary_10_1039_D1BM01663F crossref_primary_10_32604_biocell_2021_015899 crossref_primary_10_1016_j_apsb_2024_04_026 crossref_primary_10_1016_j_intimp_2015_02_012 crossref_primary_10_3736_jcim20110612 crossref_primary_10_1016_j_biocel_2015_11_010 crossref_primary_10_1111_liv_12050 crossref_primary_10_3892_mmr_2015_4452 crossref_primary_10_1021_acs_jmedchem_8b01165 crossref_primary_10_1016_j_apsb_2020_07_004 crossref_primary_10_1016_j_isci_2021_103233 crossref_primary_10_1016_j_ejpb_2021_05_027 crossref_primary_10_1002_hep_31188 crossref_primary_10_18410_jebmh_2021_563 crossref_primary_10_1016_j_toxlet_2016_09_014 crossref_primary_10_1155_2015_598179 crossref_primary_10_3389_fmolb_2021_690170 crossref_primary_10_1177_1535370213498979 crossref_primary_10_3389_fimmu_2021_666370 crossref_primary_10_1007_s10517_015_2752_9 crossref_primary_10_1007_s12033_021_00441_5 crossref_primary_10_1007_s11695_022_06416_y crossref_primary_10_1016_j_addr_2017_07_010 crossref_primary_10_1371_journal_pone_0080212 crossref_primary_10_1016_j_molimm_2020_07_012 crossref_primary_10_1016_j_jff_2021_104604 crossref_primary_10_1371_journal_pone_0089279 crossref_primary_10_3389_fcell_2021_634902 crossref_primary_10_3390_nano10101945 crossref_primary_10_1016_S1499_3872_12_60210_0 crossref_primary_10_1016_j_biopha_2017_02_010 crossref_primary_10_1016_j_jcmgh_2024_01_021 crossref_primary_10_1111_1751_2980_12042 crossref_primary_10_1016_j_biopha_2024_116490 crossref_primary_10_3389_fphar_2020_00165 crossref_primary_10_1016_j_jep_2014_03_034 crossref_primary_10_1016_j_bbadis_2012_12_013 crossref_primary_10_1089_jir_2024_0003 crossref_primary_10_1080_21655979_2022_2066756 crossref_primary_10_1155_2018_5738101 crossref_primary_10_1016_j_ejphar_2013_09_042 crossref_primary_10_1016_j_bbrc_2022_09_025 crossref_primary_10_1002_hep_26615 crossref_primary_10_1146_annurev_pathol_012615_044224 crossref_primary_10_3389_fimmu_2020_574276 crossref_primary_10_7717_peerj_16060 crossref_primary_10_1016_j_intimp_2014_09_024 crossref_primary_10_1016_j_biochi_2015_04_019 crossref_primary_10_1186_s13046_020_01568_0 crossref_primary_10_18632_aging_202211 crossref_primary_10_3390_metabo11030155 crossref_primary_10_1155_2022_1745244 crossref_primary_10_2139_ssrn_3942586 crossref_primary_10_1016_j_cellsig_2011_11_008 crossref_primary_10_3892_mmr_2021_12549 crossref_primary_10_1007_s40139_015_0094_y crossref_primary_10_3390_bioengineering10091075 crossref_primary_10_1038_srep33453 crossref_primary_10_1016_j_transproceed_2022_04_023 crossref_primary_10_1186_s13020_015_0036_y crossref_primary_10_1016_j_jgg_2022_02_013 crossref_primary_10_1073_pnas_2118068119 crossref_primary_10_1111_jcmm_14210 crossref_primary_10_1158_0008_5472_CAN_11_3317 crossref_primary_10_1080_26895293_2021_2000893 crossref_primary_10_1126_sciadv_abq2937 crossref_primary_10_1016_j_taap_2015_12_021 crossref_primary_10_1080_21655979_2022_2036902 crossref_primary_10_3389_fphar_2022_964829 crossref_primary_10_1002_advs_201801585 crossref_primary_10_1016_j_ajpath_2017_08_027 crossref_primary_10_1002_hep_32068 crossref_primary_10_1016_j_phrs_2020_104720 crossref_primary_10_1128_AAC_01347_16 crossref_primary_10_1038_s41598_017_04259_7 crossref_primary_10_1007_s10495_014_0992_1 crossref_primary_10_1186_s13069_016_0045_1 crossref_primary_10_1016_j_jhep_2013_03_016 crossref_primary_10_1177_1535370218810892 crossref_primary_10_1016_j_yexcr_2023_113521 crossref_primary_10_1016_j_addr_2021_04_003 crossref_primary_10_1186_s12967_017_1214_8 crossref_primary_10_1016_j_addr_2021_04_008 crossref_primary_10_1016_j_advms_2022_12_001 crossref_primary_10_1007_s00210_021_02192_1 crossref_primary_10_1517_14728222_2014_927443 crossref_primary_10_1073_pnas_1522163112 crossref_primary_10_1038_s41575_020_0304_x crossref_primary_10_1016_j_carbpol_2023_121637 crossref_primary_10_1038_s41374_018_0085_9 crossref_primary_10_1128_JVI_02225_16 crossref_primary_10_1016_j_taap_2015_09_028 crossref_primary_10_1016_j_jphs_2020_07_014 crossref_primary_10_1016_j_etp_2015_05_002 crossref_primary_10_1016_j_gene_2019_144233 crossref_primary_10_1134_S2079086421010059 crossref_primary_10_17816_gc610252 crossref_primary_10_1016_j_bbamcr_2013_10_010 crossref_primary_10_1002_fft2_50 crossref_primary_10_1016_j_canlet_2013_01_040 crossref_primary_10_1186_s12199_018_0739_7 crossref_primary_10_1038_s41598_021_02155_9 crossref_primary_10_1016_j_bbrc_2018_07_094 crossref_primary_10_1111_jcmm_16219 crossref_primary_10_1371_journal_pone_0274126 crossref_primary_10_1186_s12929_015_0168_5 crossref_primary_10_1371_journal_pone_0049611 crossref_primary_10_1155_2023_5444301 crossref_primary_10_3389_fphar_2022_894981 crossref_primary_10_3389_fimmu_2021_822345 crossref_primary_10_3389_fimmu_2023_1131588 crossref_primary_10_3390_jcm5010007 crossref_primary_10_3390_ijms22126404 crossref_primary_10_1002_JLB_5MR0822_733RRR crossref_primary_10_1080_09674845_2017_1278888 crossref_primary_10_1016_j_jep_2019_111910 crossref_primary_10_7744_kjoas_510205 crossref_primary_10_1002_advs_201801809 crossref_primary_10_1007_s13105_015_0452_6 crossref_primary_10_1016_j_ajpath_2012_09_006 crossref_primary_10_1016_j_bmcl_2021_127994 crossref_primary_10_33590_emj_10310892 crossref_primary_10_4254_wjh_v14_i4_744 crossref_primary_10_1016_j_jhep_2016_01_036 crossref_primary_10_3390_ijms17071122 crossref_primary_10_1093_toxres_tfac027 crossref_primary_10_1371_journal_pone_0129621 crossref_primary_10_12659_MSM_899725 crossref_primary_10_1016_j_aohep_2020_07_013 crossref_primary_10_1080_21691401_2019_1615931 crossref_primary_10_1016_j_clim_2015_03_003 crossref_primary_10_1039_C5IB00298B crossref_primary_10_1293_tox_2017_0021 crossref_primary_10_1097_RLI_0000000000000631 crossref_primary_10_4254_wjh_v13_i10_1269 crossref_primary_10_1016_j_freeradbiomed_2012_05_007 crossref_primary_10_4049_jimmunol_1400861 crossref_primary_10_3390_molecules26061786 crossref_primary_10_1039_C3TX50069A crossref_primary_10_1016_j_lfs_2018_09_051 crossref_primary_10_3906_biy_1505_32 crossref_primary_10_1097_HC9_0000000000000457 crossref_primary_10_1111_apt_12715 crossref_primary_10_1371_journal_pone_0155094 crossref_primary_10_1016_j_nucmedbio_2021_04_002 crossref_primary_10_3390_biology10050408 crossref_primary_10_3390_ijms20071745 crossref_primary_10_1096_fj_202002777RR crossref_primary_10_15252_emmm_201404246 crossref_primary_10_1016_j_bbadis_2018_01_027 crossref_primary_10_1016_j_jhep_2017_10_011 crossref_primary_10_1016_j_actbio_2014_10_002 crossref_primary_10_1016_j_cbi_2014_10_005 crossref_primary_10_1016_j_taap_2017_12_007 crossref_primary_10_1517_13543784_2011_566864 crossref_primary_10_1016_j_cnd_2014_12_002 crossref_primary_10_3748_wjg_v26_i3_279 crossref_primary_10_1080_1061186X_2024_2347365 crossref_primary_10_1111_liv_12691 crossref_primary_10_1016_j_ejphar_2014_01_074 crossref_primary_10_18632_oncotarget_11767 crossref_primary_10_1016_j_canlet_2013_07_030 crossref_primary_10_1016_j_toxlet_2021_11_014 crossref_primary_10_3390_ijms25021276 crossref_primary_10_1016_j_lfs_2020_117926 crossref_primary_10_1242_bio_018887 crossref_primary_10_3109_1061186X_2012_740674 crossref_primary_10_1002_jmri_27425 crossref_primary_10_1016_j_lfs_2024_122431 crossref_primary_10_3892_mmr_2017_8284 crossref_primary_10_1080_10520295_2017_1361549 crossref_primary_10_1016_j_cbi_2018_12_006 crossref_primary_10_1016_j_tice_2023_102198 crossref_primary_10_1586_egh_11_43 crossref_primary_10_1016_j_lfs_2021_119144 crossref_primary_10_1016_j_patbio_2013_01_005 crossref_primary_10_1371_journal_pone_0134141 crossref_primary_10_3390_ijms25052735 crossref_primary_10_3390_pathogens3030563 crossref_primary_10_1007_s11033_024_09416_6 crossref_primary_10_3389_fmed_2021_683506 crossref_primary_10_1016_j_jhep_2013_09_013 crossref_primary_10_3389_fonc_2018_00357 crossref_primary_10_1080_03008207_2018_1530770 crossref_primary_10_1111_j_1440_1746_2012_07127_x crossref_primary_10_1186_s12885_021_08428_w crossref_primary_10_1111_j_1749_6632_2012_06728_x crossref_primary_10_1038_s41419_019_1994_2 crossref_primary_10_1016_j_canlet_2014_10_021 crossref_primary_10_1016_j_yexcr_2023_113544 crossref_primary_10_1016_j_niox_2024_02_002 crossref_primary_10_1093_toxres_tfac062 crossref_primary_10_3748_wjg_v26_i40_6111 crossref_primary_10_1111_jgh_14647 crossref_primary_10_1538_expanim_17_0156 crossref_primary_10_1016_j_jconrel_2020_01_042 crossref_primary_10_1016_j_bbagen_2011_09_018 crossref_primary_10_1002_jmri_25030 crossref_primary_10_1111_jvh_13352 crossref_primary_10_3389_fphar_2018_00187 crossref_primary_10_3389_fphar_2018_01277 crossref_primary_10_1016_j_fct_2013_11_011 crossref_primary_10_1016_j_fitote_2022_105290 crossref_primary_10_3390_ph16040548 crossref_primary_10_1002_jcb_26192 crossref_primary_10_3390_cancers13102485 crossref_primary_10_3839_jabc_2023_020 crossref_primary_10_52547_phypha_26_4_8 crossref_primary_10_1016_j_cbi_2020_108945 crossref_primary_10_1016_j_intimp_2018_04_016 crossref_primary_10_1016_j_tem_2011_09_006 crossref_primary_10_1016_j_jnutbio_2015_11_005 crossref_primary_10_1002_adma_202311474 crossref_primary_10_1093_toxsci_kfaa185 crossref_primary_10_1111_jgh_12459 crossref_primary_10_1002_hep_30969 crossref_primary_10_1002_jmv_25064 crossref_primary_10_3748_wjg_v23_i7_1125 crossref_primary_10_1155_2018_8168791 crossref_primary_10_1038_srep44867 crossref_primary_10_1155_2017_3508569 crossref_primary_10_1371_journal_pone_0074605 crossref_primary_10_3390_ijms17071178 crossref_primary_10_1016_j_lfs_2019_03_064 crossref_primary_10_1002_smll_202304675 crossref_primary_10_1016_j_freeradbiomed_2022_11_011 crossref_primary_10_1016_j_dld_2019_08_014 crossref_primary_10_1016_j_cellsig_2022_110508 crossref_primary_10_1016_j_biocel_2012_12_019 crossref_primary_10_1016_j_jcmgh_2022_02_013 crossref_primary_10_1016_j_lfs_2019_04_021 crossref_primary_10_1016_j_jhep_2016_03_011 crossref_primary_10_1038_s41467_021_26410_9 crossref_primary_10_1039_C9RA04679H crossref_primary_10_1002_hep_27328 crossref_primary_10_1096_fj_201903021RR crossref_primary_10_1139_cjpp_2017_0728 crossref_primary_10_1186_s12967_016_1022_6 crossref_primary_10_1038_nm_2936 crossref_primary_10_1155_2017_4097205 crossref_primary_10_18632_oncotarget_21358 crossref_primary_10_1016_j_biopha_2022_113185 crossref_primary_10_1177_0960327116638727 crossref_primary_10_3389_fimmu_2022_994480 crossref_primary_10_1016_j_omtn_2020_08_014 crossref_primary_10_1172_JCI65179 crossref_primary_10_1016_j_biopha_2020_110586 crossref_primary_10_1016_j_bbadis_2021_166235 crossref_primary_10_1016_j_addr_2017_05_018 crossref_primary_10_1016_j_lfs_2019_04_037 crossref_primary_10_4254_wjh_v4_i12_356 crossref_primary_10_1016_j_addr_2017_05_016 crossref_primary_10_1089_hum_2016_006 crossref_primary_10_1016_j_ijbiomac_2023_123639 crossref_primary_10_5812_hepatmon_114050 crossref_primary_10_1021_acsami_2c19269 crossref_primary_10_1146_annurev_pathol_052016_100322 crossref_primary_10_1016_S1665_2681_19_30785_9 crossref_primary_10_1186_s13148_015_0056_6 crossref_primary_10_3390_ijms20071723 crossref_primary_10_1097_MEG_0000000000000656 crossref_primary_10_1152_ajpcell_00230_2013 crossref_primary_10_3748_wjg_v22_i17_4338 crossref_primary_10_1038_labinvest_2015_59 crossref_primary_10_1016_j_bbrc_2019_02_065 crossref_primary_10_18632_aging_101124 crossref_primary_10_1111_jcmm_16267 crossref_primary_10_1007_s00210_014_0959_3 crossref_primary_10_3390_molecules27030654 crossref_primary_10_1111_bph_14873 crossref_primary_10_3389_fmolb_2023_1160851 crossref_primary_10_3389_fphar_2021_771459 crossref_primary_10_1007_s11655_015_2127_0 crossref_primary_10_1007_s12016_012_8323_1 crossref_primary_10_1016_j_bbamcr_2015_11_008 crossref_primary_10_1016_j_pharmthera_2021_107941 crossref_primary_10_1007_s11655_013_1597_1 crossref_primary_10_1007_s11302_017_9570_7 crossref_primary_10_1007_s00018_012_1046_x crossref_primary_10_1016_j_taap_2017_12_010 crossref_primary_10_1038_cr_2015_84 crossref_primary_10_3390_nu10020117 crossref_primary_10_1016_j_pharep_2017_11_017 crossref_primary_10_15324_kjcls_2015_47_4_251 crossref_primary_10_1111_hepr_12415 crossref_primary_10_1007_s12011_019_1641_x crossref_primary_10_1111_jgh_12017 crossref_primary_10_1007_s12072_023_10523_y crossref_primary_10_3389_fphys_2021_676722 crossref_primary_10_1016_j_prp_2016_11_004 crossref_primary_10_3892_mmr_2014_2036 crossref_primary_10_1038_s41419_023_06043_0 crossref_primary_10_1517_13543784_2015_997874 crossref_primary_10_1186_s10020_022_00508_2 crossref_primary_10_3390_cells11101715 crossref_primary_10_1186_s13071_017_2228_z crossref_primary_10_32604_csse_2023_036534 crossref_primary_10_1016_j_surg_2016_04_025 crossref_primary_10_1016_j_colsurfb_2016_02_029 crossref_primary_10_1016_j_cellsig_2021_110224 crossref_primary_10_1002_ijc_29703 crossref_primary_10_1016_j_ejmech_2022_114685 crossref_primary_10_5115_acb_2016_49_3_189 crossref_primary_10_1016_j_biopha_2023_115673 crossref_primary_10_1038_s41597_023_02257_1 crossref_primary_10_1002_hep_27378 crossref_primary_10_1007_s10517_016_3526_8 crossref_primary_10_3390_molecules29020417 crossref_primary_10_1016_j_dld_2012_02_015 crossref_primary_10_1016_j_ejbas_2014_12_005 crossref_primary_10_1016_j_febslet_2015_04_010 crossref_primary_10_1038_labinvest_2017_65 crossref_primary_10_1038_s41598_020_65069_y crossref_primary_10_1039_D1FO04404D crossref_primary_10_3389_fphar_2022_981817 crossref_primary_10_7554_eLife_74513 crossref_primary_10_3389_fphar_2022_788388 crossref_primary_10_1002_hep_30770 crossref_primary_10_4254_wjh_v16_i2_264 crossref_primary_10_1002_cbdv_202200401 crossref_primary_10_1016_j_jep_2024_117963 crossref_primary_10_1007_s12072_014_9526_8 crossref_primary_10_1016_j_ica_2014_03_027 crossref_primary_10_1016_j_bpg_2011_02_007 crossref_primary_10_1155_2015_595467 crossref_primary_10_1155_2021_3206982 crossref_primary_10_1016_j_ecoenv_2022_114308 crossref_primary_10_1134_S0026893316020278 crossref_primary_10_1016_j_nano_2018_12_008 crossref_primary_10_3390_nu14091756 crossref_primary_10_1016_j_bbadis_2014_10_001 crossref_primary_10_1016_j_bioorg_2024_107113 crossref_primary_10_1124_mol_114_095141 crossref_primary_10_1097_MEG_0000000000000631 crossref_primary_10_1016_j_ejrad_2022_110178 crossref_primary_10_1016_j_jep_2021_113938 crossref_primary_10_1016_j_lfs_2014_05_012 crossref_primary_10_1021_acs_jafc_1c01851 crossref_primary_10_1371_journal_pone_0132119 crossref_primary_10_1002_biof_1546 crossref_primary_10_1002_cbin_10706 crossref_primary_10_1038_s41596_021_00509_1 crossref_primary_10_1073_pnas_1909145117 crossref_primary_10_1177_0960327114531992 crossref_primary_10_3389_fmed_2019_00312 crossref_primary_10_1007_s13273_016_0031_0 crossref_primary_10_1097_MD_0000000000018458 crossref_primary_10_1128_JVI_01962_13 crossref_primary_10_1016_j_yexcr_2021_112721 crossref_primary_10_1007_s00795_024_00395_y crossref_primary_10_1016_j_jep_2022_116056 crossref_primary_10_1016_j_taap_2012_11_007 crossref_primary_10_1128_JVI_00974_13 crossref_primary_10_1016_j_intimp_2017_09_013 crossref_primary_10_3389_fimmu_2023_1259246 crossref_primary_10_1111_hepr_12215 crossref_primary_10_1155_2017_5603216 crossref_primary_10_1080_15384101_2016_1152435 crossref_primary_10_1111_bph_15752 crossref_primary_10_3727_105221615X14181438356210 crossref_primary_10_1080_01480545_2019_1571502 crossref_primary_10_1016_j_taap_2019_114748 crossref_primary_10_3803_EnM_2022_1412 crossref_primary_10_1152_ajpendo_00427_2019 crossref_primary_10_1007_s00018_015_1970_7 crossref_primary_10_1016_j_ejrad_2018_02_032 crossref_primary_10_1016_j_mri_2015_06_022 crossref_primary_10_1152_ajpcell_00423_2014 crossref_primary_10_1016_j_metabol_2016_10_002 crossref_primary_10_1186_s12967_014_0341_8 |
| ContentType | Journal Article |
| DBID | CGR CUY CVF ECM EIF NPM |
| DOI | 10.1146/annurev-pathol-011110-130246 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) |
| DatabaseTitleList | MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | no_fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1553-4014 |
| ExternalDocumentID | 21073339 |
| Genre | Journal Article Review |
| GroupedDBID | --- -QD -QH 0R~ 1KX 39C 4.4 51A 53G 5FA 5FB 5FC 5FD 5FE 5FF 5FH 6J9 70K 70N 70Q 70S 70W 79. 7A. 7B- 8NG AABJL AAGWO AALHT AALUV AAOHI AARJV AAWJP AAYIS ABDOG ABGRM ABIPL ABJNI ABKGM ABVYV ABZNY ACAHA ACDVT ACGFS ACMXS ACQCJ ACRLM ACSOE ADEJD ADHEY ADLON ADNJN ADSVE AEAIQ AEKBM AEPIK AEWIE AFCZG AFERR AFKDQ AFKEJ AFONB AHIXL AHKZM AHVNO AICBU AIDEK AIJFW AJAAW ALAFQ ALMA_UNASSIGNED_HOLDINGS AMTJG AOUBY AQQLW ATAUN B9D B9E B9F B9G B9H B9L B9N BCFVH BJPMW BMYRD BR6 CGR CUY CVF EBS ECM EIF EJD F-Q F-S F-V F-X F-Y F-Z F5P FIWKU FIXEU FMZAJ FQMFW FT0 FU. FUEKT FXG GJQJI GLOEX GNDDA GOAVI GQXMV HZ~ H~9 J1V M22 N9A NPM O9- P0P RAR RAV ZYWBE |
| ID | FETCH-LOGICAL-c388t-c7658238655866e6201c47e159ac857f38d534a66d5bfa480b50d894e85c8e812 |
| IngestDate | Tue Oct 15 23:38:32 EDT 2024 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c388t-c7658238655866e6201c47e159ac857f38d534a66d5bfa480b50d894e85c8e812 |
| PMID | 21073339 |
| ParticipantIDs | pubmed_primary_21073339 |
| PublicationCentury | 2000 |
| PublicationDate | 2011-02-28 |
| PublicationDateYYYYMMDD | 2011-02-28 |
| PublicationDate_xml | – month: 02 year: 2011 text: 2011-02-28 day: 28 |
| PublicationDecade | 2010 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States |
| PublicationTitle | Annual review of pathology |
| PublicationTitleAlternate | Annu Rev Pathol |
| PublicationYear | 2011 |
| SSID | ssj0043688 |
| Score | 2.6019473 |
| SecondaryResourceType | review_article |
| Snippet | Liver fibrosis is a major cause of morbidity and mortality worldwide due to chronic viral hepatitis and, more recently, from fatty liver disease associated... |
| SourceID | pubmed |
| SourceType | Index Database |
| StartPage | 425 |
| SubjectTerms | Humans Liver - immunology Liver - pathology Liver Cirrhosis - etiology Liver Cirrhosis - immunology Liver Cirrhosis - pathology Signal Transduction - immunology |
| Title | Pathogenesis of liver fibrosis |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/21073339 |
| Volume | 6 |
| hasFullText | |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3NS8MwFA9-wPAifn-PHnaTaLckbXoUcQ5xw8Mmu400SUdB2-F28q_3JWm3OnWol1IaWpL8mpffe-T9HkINASwjEVpiTaU00aoIC0ZbsK7MfhEZlSeTnNztBZ0BfRiy4aJknc0umcVX8v3bvJL_oArPAFeTJfsHZOcfhQdwD_jCFRCG668wfgL6lo-NtXKqIi_mkMVlAh5wPk2nVd5ZyOgvElVMJeJPEfVOGVDG99oSyuf0bZxm6dxst8GpVmW81Co6PFZDBiYGOk_B1oWZYwQ8R5e-WdrBqh2jLhv5q32tCgtj11VsytWbMx4E9vug-hrM1uTVzj04liEhTrZodeuS-nXZtI7WQ25Kc_RMNMbttEY8n9dQo-jY9apuWdFn96klB8ISif4O2i48AO_GwbmL1nS2h2rd4ozDPqpXUfXyxLOoeiWqB2jQvuvfdnBRxQJLwvkMyxBIXsuUVmU8CHQAgEgaaqCRQnIWJoQrRqgIAsXiRFDux8xXPKKaM8k18K9DtJHlmT5GXpMDwRacRiRhsLRYHCnSFL4fR1Jp7asTdORGNpo4qZJROebTH1vO0NbiFzlHmwmsDX0BRGsW1-1sfwBh_iTE |
| link.rule.ids | 780 |
| linkProvider | National Library of Medicine |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Pathogenesis+of+liver+fibrosis&rft.jtitle=Annual+review+of+pathology&rft.au=Hernandez-Gea%2C+Virginia&rft.au=Friedman%2C+Scott+L&rft.date=2011-02-28&rft.eissn=1553-4014&rft.volume=6&rft.spage=425&rft_id=info:doi/10.1146%2Fannurev-pathol-011110-130246&rft_id=info%3Apmid%2F21073339&rft_id=info%3Apmid%2F21073339&rft.externalDocID=21073339 |