Silane-modified surfaces in specific antibody-mediated cell recognition

• Published in: Folia histochemica et cytobiologica Vol. 52; no. 3; pp. 250 - 255
• Main Authors: Sterzynska, Karolina, Budna, Joanna, Frydrych-Tomczak, Emilia, Hreczycho, Grzegorz, Malinska, Agnieszka, Maciejewski, Hieronim, Zabel, Maciej
• Format: Journal Article
• Language: English
• Published: Poland Wydawnictwo Via Medica 01.01.2014
• Subjects: Adenocarcinoma; Aminopropyltriethoxysilane; Animals; Antibodies; Antibodies - metabolism; Antibodies, Immobilized - metabolism; Antigens; Binding; Biological effects; Cell Line, Tumor; Cell recognition; Colon; Contact angle; Embryo fibroblasts; Enumeration; Fibroblasts - cytology; Fibroblasts - metabolism; Fluorescent Antibody Technique; Humans; Immobilization; Immunoassay; Immunofluorescence; Mice; Molecular Structure; NIH 3T3 Cells; Propylamines; Protein Binding; Recognition; Silanes; Silanes - chemistry; Silanes - metabolism; Solid surfaces; Surface Properties

The immobilization of antibodies on various surfaces has been the subject of advanced research in various immunoassay-based diagnostic devices. The physical and chemical stabilities of the immobilized antibodies on a solid surface still cause many problems because upon immobilizing antibody molecule...