Making precision medicine personal for cystic fibrosis

• Published in: Science (American Association for the Advancement of Science) Vol. 365; no. 6450; pp. 220 - 221
• Main Authors: Manfredi, Candela, Tindall, Janice M., Hong, Jeong S., Sorscher, Eric J.
• Format: Journal Article
• Language: English
• Published: United States American Association for the Advancement of Science 19.07.2019; The American Association for the Advancement of Science
• Subjects: Conductance; Cystic fibrosis; Cystic Fibrosis - genetics; Cystic Fibrosis - therapy; Cystic Fibrosis Transmembrane Conductance Regulator - genetics; Drug therapy; Epithelial cells; Humans; Ion channels; Lungs; Medicine; Modulators; Mutation; Pancreas; PERSPECTIVES; Pharmacology; Precision medicine; Precision Medicine - methods

Molecular defects in the cystic fibrosis gene prompt creative approaches to treatment Cystic fibrosis (CF) is an inherited, life-threatening disease that primarily involves exocrine tissues (such as lungs, pancreas, and liver) for which highly active pharmacotherapies have recently emerged. More tha...